pc2, Gsp_010792 (mRNA) Girardia sp.

Overview


Name	pc2
Unique Name	Gsp_010792
Type	mRNA
Organism	Girardia sp. (Girardia sp.)
Sequence length	2205

Analyses

This mRNA is derived from or has results from the following analyses


Analysis Name	Date Performed
Girardia sp. Transcriptome	2016-03-03
Girardia Sp Translation	2016-04-28
Girardia Sp. BLASTX Human	2016-03-08
Girardia Sp. BLASTX Swissprot Uniprot	2016-03-08
Girardia Sp. BLASTX Drosophila melanogaster	2016-03-09
Girardia Sp. BLASTX Schmidtea mediterranea	2016-03-09
Girardia Sp CDS	2016-05-06

Homology

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BLAST of pc2 vs. RefSeq Human
Match: gi|20336244|ref|NP_002585.2| (neuroendocrine convertase 2 isoform 1 preproprotein [Homo sapiens])

HSP 1 Score: 686.411 bits (1770), Expect = 0.000e+0
Identity = 370/617 (59.97%), Postives = 438/617 (70.99%), Query Frame = 2

Query:   98 LLFLIQIYTIYGK-IVTNQWHVRLHDPGTHDLANKVAQETGFSLLRNHIQSPNEFVYHHKAVPHVSSIPSWNHHKVLLSHPLVKEAKQVEGFIRKKRGFKPIKKQDRIPLPTINKKGIPGRGKTENIKENMKLPTDPLFSKEWYIRNTGQADGVKDLDLNVLSAWAQGITGKGVTTAIMDDGIDYLHPDLSKNYNAESSYDFSSNDPYPFPRYTDDWFNSHGTRCAGEISAERDNGICGVGVAYNSKIAGLRMLDQPYMTDLIEAAAMSYDRDNIDIYSASWGPTDDGRTVDGPRNETMRAIVEGVNKGRKGKGSIYVWASXXXXXXXXXXXXXXXXSMWTISINSATNDGETASYDESCSSTLASTFSNGKAWFSLDAGVGTVDLYGQCTLHHSGTSAAAPEAAGVFALALEANSNIGWRDMQHLTVLTSKXXXXXXXXXXXXWTINGAGLEFNHLFGYGVLDAGDMVRVAKKWVNVPERFHCIAGQINKRYRFNVTKALILEIDTDACKSDTGHRVNYLEHVQAFISVKASRRGDITMFLTSPMGTTSMILSHRPKDDDSTRGFTKWPFMTTHTWGENPRGKWRLTIMFDTKDPLSQGIFSEWVLVLHGTQNRPY 1945
             LF + ++    + + TN + V LH  G  D A +VA E GF + R    +   + ++H  +       S +H + L   P VK A Q EGF RKKRG++ I +                      I  NM    DPLF+K+WY+ NTGQADG   LDLNV  AW  G TGKGVT  IMDDGIDYLHPDL+ NYNAE+SYDFSSNDPYP+PRYTDDWFNSHGTRCAGE+SA  +N ICGVGVAYNSK+AG+RMLDQP+MTD+IEA+++S+    IDIYSASWGPTD+G+TVDGPR  T++A+ +GVNKGR GKGSIYVWASGDGG+ DDCNCDGYA+SMWTISINSA NDG TA YDESCSSTLASTFSNG+   + +AGV T DLYG CTL HSGTSAAAPEAAGVFALALEAN  + WRDMQHLTVLTSK       D  H W  NG GLEFNHLFGYGVLDAG MV++AK W  VPERFHC+ G +    +   T  L+L + TDAC+      V YLEHVQA I+V A+RRGD+ + +TSPMGT S++LS RP+DDDS  GF KWPFMTTHTWGE+ RG W L + F    P  +G+  EW L+LHGTQ+ PY
Sbjct:   15 FLFCVMVFASAERPVFTNHFLVELH-KGGEDKARQVAAEHGFGV-RKLPFAEGLYHFYHNGLAKAKRRRSLHHKQQLERDPRVKMALQQEGFDRKKRGYRDINE----------------------IDINM---NDPLFTKQWYLINTGQADGTPGLDLNVAEAWELGYTGKGVTIGIMDDGIDYLHPDLASNYNAEASYDFSSNDPYPYPRYTDDWFNSHGTRCAGEVSAAANNNICGVGVAYNSKVAGIRMLDQPFMTDIIEASSISHMPQLIDIYSASWGPTDNGKTVDGPRELTLQAMADGVNKGRGGKGSIYVWASGDGGSYDDCNCDGYASSMWTISINSAINDGRTALYDESCSSTLASTFSNGRK-RNPEAGVATTDLYGNCTLRHSGTSAAAPEAAGVFALALEANLGLTWRDMQHLTVLTSK--RNQLHDEVHQWRRNGVGLEFNHLFGYGVLDAGAMVKMAKDWKTVPERFHCVGGSVQDPEKIPSTGKLVLTLTTDACEGKENF-VRYLEHVQAVITVNATRRGDLNINMTSPMGTKSILLSRRPRDDDSKVGFDKWPFMTTHTWGEDARGTWTLELGFVGSAP-QKGVLKEWTLMLHGTQSAPY 599

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BLAST of pc2 vs. RefSeq Human
Match: gi|320118926|ref|NP_001188457.1| (neuroendocrine convertase 2 isoform 3 [Homo sapiens])

HSP 1 Score: 684.871 bits (1766), Expect = 0.000e+0
Identity = 368/603 (61.03%), Postives = 432/603 (71.64%), Query Frame = 2

Query:  137 IVTNQWHVRLHDPGTHDLANKVAQETGFSLLRNHIQSPNEFVYHHKAVPHVSSIPSWNHHKVLLSHPLVKEAKQVEGFIRKKRGFKPIKKQDRIPLPTINKKGIPGRGKTENIKENMKLPTDPLFSKEWYIRNTGQADGVKDLDLNVLSAWAQGITGKGVTTAIMDDGIDYLHPDLSKNYNAESSYDFSSNDPYPFPRYTDDWFNSHGTRCAGEISAERDNGICGVGVAYNSKIAGLRMLDQPYMTDLIEAAAMSYDRDNIDIYSASWGPTDDGRTVDGPRNETMRAIVEGVNKGRKGKGSIYVWASXXXXXXXXXXXXXXXXSMWTISINSATNDGETASYDESCSSTLASTFSNGKAWFSLDAGVGTVDLYGQCTLHHSGTSAAAPEAAGVFALALEANSNIGWRDMQHLTVLTSKXXXXXXXXXXXXWTINGAGLEFNHLFGYGVLDAGDMVRVAKKWVNVPERFHCIAGQINKRYRFNVTKALILEIDTDACKSDTGHRVNYLEHVQAFISVKASRRGDITMFLTSPMGTTSMILSHRPKDDDSTRGFTKWPFMTTHTWGENPRGKWRLTIMFDTKDPLSQGIFSEWVLVLHGTQNRPY 1945
            + TN + V LH  G  D A +VA E GF + R    +   + ++H  +       S +H + L   P VK A Q EGF RKKRG++ I +                      I  NM    DPLF+K+WY+ NTGQADG   LDLNV  AW  G TGKGVT  IMDDGIDYLHPDL+ NYNAE+SYDFSSNDPYP+PRYTDDWFNSHGTRCAGE+SA  +N ICGVGVAYNSK+AG+RMLDQP+MTD+IEA+++S+    IDIYSASWGPTD+G+TVDGPR  T++A+ +GVNKGR GKGSIYVWASGDGG+ DDCNCDGYA+SMWTISINSA NDG TA YDESCSSTLASTFSNG+   + +AGV T DLYG CTL HSGTSAAAPEAAGVFALALEAN  + WRDMQHLTVLTSK       D  H W  NG GLEFNHLFGYGVLDAG MV++AK W  VPERFHC+ G +    +   T  L+L + TDAC+      V YLEHVQA I+V A+RRGD+ + +TSPMGT S++LS RP+DDDS  GF KWPFMTTHTWGE+ RG W L + F    P  +G+  EW L+LHGTQ+ PY
Sbjct:   10 VFTNHFLVELH-KGGEDKARQVAAEHGFGV-RKLPFAEGLYHFYHNGLAKAKRRRSLHHKQQLERDPRVKMALQQEGFDRKKRGYRDINE----------------------IDINM---NDPLFTKQWYLINTGQADGTPGLDLNVAEAWELGYTGKGVTIGIMDDGIDYLHPDLASNYNAEASYDFSSNDPYPYPRYTDDWFNSHGTRCAGEVSAAANNNICGVGVAYNSKVAGIRMLDQPFMTDIIEASSISHMPQLIDIYSASWGPTDNGKTVDGPRELTLQAMADGVNKGRGGKGSIYVWASGDGGSYDDCNCDGYASSMWTISINSAINDGRTALYDESCSSTLASTFSNGRK-RNPEAGVATTDLYGNCTLRHSGTSAAAPEAAGVFALALEANLGLTWRDMQHLTVLTSK--RNQLHDEVHQWRRNGVGLEFNHLFGYGVLDAGAMVKMAKDWKTVPERFHCVGGSVQDPEKIPSTGKLVLTLTTDACEGKENF-VRYLEHVQAVITVNATRRGDLNINMTSPMGTKSILLSRRPRDDDSKVGFDKWPFMTTHTWGEDARGTWTLELGFVGSAP-QKGVLKEWTLMLHGTQSAPY 580

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BLAST of pc2 vs. RefSeq Human
Match: gi|320118928|ref|NP_001188458.1| (neuroendocrine convertase 2 isoform 2 preproprotein [Homo sapiens])

HSP 1 Score: 667.152 bits (1720), Expect = 0.000e+0
Identity = 364/617 (59.00%), Postives = 427/617 (69.21%), Query Frame = 2

Query:   98 LLFLIQIYTIYGK-IVTNQWHVRLHDPGTHDLANKVAQETGFSLLRNHIQSPNEFVYHHKAVPHVSSIPSWNHHKVLLSHPLVKEAKQVEGFIRKKRGFKPIKKQDRIPLPTINKKGIPGRGKTENIKENMKLPTDPLFSKEWYIRNTGQADGVKDLDLNVLSAWAQGITGKGVTTAIMDDGIDYLHPDLSKNYNAESSYDFSSNDPYPFPRYTDDWFNSHGTRCAGEISAERDNGICGVGVAYNSKIAGLRMLDQPYMTDLIEAAAMSYDRDNIDIYSASWGPTDDGRTVDGPRNETMRAIVEGVNKGRKGKGSIYVWASXXXXXXXXXXXXXXXXSMWTISINSATNDGETASYDESCSSTLASTFSNGKAWFSLDAGVGTVDLYGQCTLHHSGTSAAAPEAAGVFALALEANSNIGWRDMQHLTVLTSKXXXXXXXXXXXXWTINGAGLEFNHLFGYGVLDAGDMVRVAKKWVNVPERFHCIAGQINKRYRFNVTKALILEIDTDACKSDTGHRVNYLEHVQAFISVKASRRGDITMFLTSPMGTTSMILSHRPKDDDSTRGFTKWPFMTTHTWGENPRGKWRLTIMFDTKDPLSQGIFSEWVLVLHGTQNRPY 1945
             LF + ++    + + TN + V LH  G  D A +VA E GF + +                                    VK A Q EGF RKKRG++ I +                      I  NM    DPLF+K+WY+ NTGQADG   LDLNV  AW  G TGKGVT  IMDDGIDYLHPDL+ NYNAE+SYDFSSNDPYP+PRYTDDWFNSHGTRCAGE+SA  +N ICGVGVAYNSK+AG+RMLDQP+MTD+IEA+++S+    IDIYSASWGPTD+G+TVDGPR  T++A+ +GVNKGR GKGSIYVWASGDGG+ DDCNCDGYA+SMWTISINSA NDG TA YDESCSSTLASTFSNG+   + +AGV T DLYG CTL HSGTSAAAPEAAGVFALALEAN  + WRDMQHLTVLTSK       D  H W  NG GLEFNHLFGYGVLDAG MV++AK W  VPERFHC+ G +    +   T  L+L + TDAC+    + V YLEHVQA I+V A+RRGD+ + +TSPMGT S++LS RP+DDDS  GF KWPFMTTHTWGE+ RG W L + F    P  +G+  EW L+LHGTQ+ PY
Sbjct:   15 FLFCVMVFASAERPVFTNHFLVELH-KGGEDKARQVAAEHGFGVRK------------------------------------VKMALQQEGFDRKKRGYRDINE----------------------IDINMN---DPLFTKQWYLINTGQADGTPGLDLNVAEAWELGYTGKGVTIGIMDDGIDYLHPDLASNYNAEASYDFSSNDPYPYPRYTDDWFNSHGTRCAGEVSAAANNNICGVGVAYNSKVAGIRMLDQPFMTDIIEASSISHMPQLIDIYSASWGPTDNGKTVDGPRELTLQAMADGVNKGRGGKGSIYVWASGDGGSYDDCNCDGYASSMWTISINSAINDGRTALYDESCSSTLASTFSNGRK-RNPEAGVATTDLYGNCTLRHSGTSAAAPEAAGVFALALEANLGLTWRDMQHLTVLTSK--RNQLHDEVHQWRRNGVGLEFNHLFGYGVLDAGAMVKMAKDWKTVPERFHCVGGSVQDPEKIPSTGKLVLTLTTDACEGKE-NFVRYLEHVQAVITVNATRRGDLNINMTSPMGTKSILLSRRPRDDDSKVGFDKWPFMTTHTWGEDARGTWTLELGFVGSAP-QKGVLKEWTLMLHGTQSAPY 564

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BLAST of pc2 vs. RefSeq Human
Match: gi|20336242|ref|NP_000430.3| (neuroendocrine convertase 1 isoform 1 preproprotein [Homo sapiens])

HSP 1 Score: 421.009 bits (1081), Expect = 1.796e-134
Identity = 249/604 (41.23%), Postives = 360/604 (59.60%), Query Frame = 2

Query:  146 NQWHVRLHDPGTHDLANKVAQETGFSLLRNHIQSPNEFVYHHKAVPHVSSIPSWNHHKVLLSHPLVKEAKQVEGFIRKKRGFKPIKKQDRIPLPTINKKGIPGRGKTENIKEN-MKLPTDPLFSKEWYIRNTGQADGVKDLDLNVLSAWAQGITGKGVTTAIMDDGIDYLHPDLSKNYNAESSYDFSSNDPYPFPRYTDDWFNSHGTRCAGEISAERDNGICGVGVAYNSKIAGLRMLDQPYMTDLIEAAAMSYDRDNIDIYSASWGPTDDGRTVDGPRNETMRAIVEGVNKGRKGKGSIYVWAS-XXXXXXXXXXXXXXXXSMWTISINSATNDGETASYDESCSSTLASTFSNGKAWFSLDAGVGTVDLYGQCTLHHSGTSAAAPEAAGVFALALEANSNIGWRDMQHLTVLTSKXXXXXXXXXXXXWTINGAGLEFNHLFGYGVLDAGDMVRVA--KKWVNVPERFHCIAGQINKRYR-FNVTKALILEIDTDACKSDTGHRVNYLEHVQAFISVKASRRGDITMFLTSPMGTTSMILSHRPKDDDSTRGFTKWPFMTTHTWGENPRGKWRLTIMFDTKDPLSQGIFSEWVLVLHGTQNRP 1942
            N+W   +  PG  + A+ +A+E G+ LL       N +++ HK  P  S   +++  K L     V  A+Q     R KR                             ++++ + L  DP+++++WY+++T     +  LDL+V+  W +GITGKGV   ++DDG+++ H D+  NY+ E+SYDF+ ND  PFPRY     N HGTRCAGEI+ + +N  CGVGVAYNSK+ G+RMLD   +TD IEA+++ ++  ++DIYSASWGP DDG+TV+GP     +A   GV +GR+GKGSI+VWAS   G   D+C+CDGY  S++TISI+SA+  G +  Y E CSSTLA+++S+G      D  + + DL+  CT  H+GTSA+AP AAG+FALALEAN N+ WRDMQHL V TS+            W  NGAGL  N  FG+G+L+A  +V +A  + W +VPE+  C+    +   R       +I+EI T AC+    + +  LEHVQ   +++ SRRGD+ + LTS  GT++++L+ R + D S  GF  W FM+ HTWGENP G W L I   +    ++G    W L+LHGT ++P
Sbjct:   33 NEWAAEI--PGGPEAASAIAEELGYDLLGQIGSLENHYLFKHKNHPRRSRRSAFHITKRLSDDDRVIWAEQQYEKERSKRSA---------------------------LRDSALNLFNDPMWNQQWYLQDTRMTAALPKLDLHVIPVWQKGITGKGVVITVLDDGLEWNHTDIYANYDPEASYDFNDNDHDPFPRYDPTNENKHGTRCAGEIAMQANNHKCGVGVAYNSKVGGIRMLDG-IVTDAIEASSIGFNPGHVDIYSASWGPNDDGKTVEGPGRLAQKAFEYGVKQGRQGKGSIFVWASGNGGRQGDNCDCDGYTDSIYTISISSASQQGLSPWYAEKCSSTLATSYSSGDY---TDQRITSADLHNDCTETHTGTSASAPLAAGIFALALEANPNLTWRDMQHLVVWTSE---YDPLANNPGWKKNGAGLMVNSRFGFGLLNAKALVDLADPRTWRSVPEKKECVVKDNDFEPRALKANGEVIIEIPTRACEGQE-NAIKSLEHVQFEATIEYSRRGDLHVTLTSAAGTSTVLLAERER-DTSPNGFKNWDFMSVHTWGENPIGTWTLRITDMSGRIQNEGRIVNWKLILHGTSSQP 598

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BLAST of pc2 vs. RefSeq Human
Match: gi|4505579|ref|NP_002560.1| (furin preproprotein [Homo sapiens])

HSP 1 Score: 416.001 bits (1068), Expect = 4.086e-132
Identity = 251/600 (41.83%), Postives = 345/600 (57.50%), Query Frame = 2

Query:  134 KIVTNQWHVRLHDPGTHDLANKVAQETGFSLLRNHIQSPNEFVYHHKAVPHVSSIPSWNHHKVLLSHPLVKEAKQVEGFIRKKRGFKPIKKQDRIPLPTINKKGIPGRGKTENIKENMKLPTDPLFSKEWYIRNTGQADGVKDLDLNVLSAWAQGITGKGVTTAIMDDGIDYLHPDLSKNYNAESSYDFSSNDPYPFPRYTDDWFNSHGTRCAGEISAERDNGICGVGVAYNSKIAGLRMLDQPYMTDLIEAAAMSYDRDNIDIYSASWGPTDDGRTVDGPRNETMRAIVEGVNKGRKGKGSIYVWASXXXXXXXXXXXXXX-XXSMWTISINSATNDGETASYDESCSSTLASTFSNGKAWFSLDAGVGTVDLYGQCTLHHSGTSAAAPEAAGVFALALEANSNIGWRDMQHLTVLTSKXXXXXXXXXXXXWTINGAGLEFNHLFGYGVLDAGDMVRVAKKWVNVPERFHCIAGQINKRYRFNVTKALILEIDTDACKSDTGHRVNYLEHVQAFISVKASRRGDITMFLTSPMGTTSMILSHRPKDDDSTRGFTKWPFMTTHTWGENPRGKWRLTIMFDTKDPLSQGIFSEWVLVLHGT 1930
            K+ TN W VR+  PG   +AN VA++ GF  L       + + + H+ V   S  P    H  L   P V+  +Q     R KR                               +  + PTDP F ++WY+       GV   DLNV +AWAQG TG G+  +I+DDGI+  HPDL+ NY+  +S+D +  DP P PRYT    N HGTRCAGE++A  +NG+CGVGVAYN++I G+RMLD   +TD +EA ++  + ++I IYSASWGP DDG+TVDGP      A   GV++GR G GSI+VWASG+GG   D         S++T+SI+SAT  G    Y E+CSSTLA+T+S+G      +  + T DL  +CT  H+GTSA+AP AAG+ AL LEAN N+ WRDMQHL V TSK          ++W  NG G + +H +GYG+LDAG MV +A+ W  V  +  CI   + +    ++ K L +     AC  +  H +  LEH QA +++  +RRGD+ + L SPMGT S +L+ RP  D S  GF  W FMTTH+W E+P G+W L I  +T +  + G  +++ LVL+GT
Sbjct:   28 KVFTNTWAVRI--PGGPAVANSVARKHGFLNLGQIFG--DYYHFWHRGVTKRSLSPHRPRHSRLQREPQVQWLEQQVAKRRTKR-------------------------------DVYQEPTDPKFPQQWYL------SGVTQRDLNVKAAWAQGYTGHGIVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDPDPQPRYTQMNDNRHGTRCAGEVAAVANNGVCGVGVAYNARIGGVRMLDG-EVTDAVEARSLGLNPNHIHIYSASWGPEDDGKTVDGPARLAEEAFFRGVSQGRGGLGSIFVWASGNGGREHDSCNCDGYTNSIYTLSISSATQFGNVPWYSEACSSTLATTYSSGN---QNEKQIVTTDLRQKCTESHTGTSASAPLAAGIIALTLEANKNLTWRDMQHLVVQTSK----PAHLNANDWATNGVGRKVSHSYGYGLLDAGAMVALAQNWTTVAPQRKCIIDILTEPK--DIGKRLEVRKTVTACLGEPNH-ITRLEHAQARLTLSYNRRGDLAIHLVSPMGTRSTLLAARPH-DYSADGFNDWAFMTTHSWDEDPSGEWVLEIE-NTSEANNYGTLTKFTLVLYGT 573

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BLAST of pc2 vs. uniprot
Match: gi|13124785|sp|P16519|NEC2_HUMAN (RecName: Full=Neuroendocrine convertase 2; Short=NEC 2; AltName: Full=KEX2-like endoprotease 2; AltName: Full=Prohormone convertase 2; AltName: Full=Proprotein convertase 2; Short=PC2; Flags: Precursor)

HSP 1 Score: 686.411 bits (1770), Expect = 0.000e+0
Identity = 370/617 (59.97%), Postives = 438/617 (70.99%), Query Frame = 2

Query:   98 LLFLIQIYTIYGK-IVTNQWHVRLHDPGTHDLANKVAQETGFSLLRNHIQSPNEFVYHHKAVPHVSSIPSWNHHKVLLSHPLVKEAKQVEGFIRKKRGFKPIKKQDRIPLPTINKKGIPGRGKTENIKENMKLPTDPLFSKEWYIRNTGQADGVKDLDLNVLSAWAQGITGKGVTTAIMDDGIDYLHPDLSKNYNAESSYDFSSNDPYPFPRYTDDWFNSHGTRCAGEISAERDNGICGVGVAYNSKIAGLRMLDQPYMTDLIEAAAMSYDRDNIDIYSASWGPTDDGRTVDGPRNETMRAIVEGVNKGRKGKGSIYVWASXXXXXXXXXXXXXXXXSMWTISINSATNDGETASYDESCSSTLASTFSNGKAWFSLDAGVGTVDLYGQCTLHHSGTSAAAPEAAGVFALALEANSNIGWRDMQHLTVLTSKXXXXXXXXXXXXWTINGAGLEFNHLFGYGVLDAGDMVRVAKKWVNVPERFHCIAGQINKRYRFNVTKALILEIDTDACKSDTGHRVNYLEHVQAFISVKASRRGDITMFLTSPMGTTSMILSHRPKDDDSTRGFTKWPFMTTHTWGENPRGKWRLTIMFDTKDPLSQGIFSEWVLVLHGTQNRPY 1945
             LF + ++    + + TN + V LH  G  D A +VA E GF + R    +   + ++H  +       S +H + L   P VK A Q EGF RKKRG++ I +                      I  NM    DPLF+K+WY+ NTGQADG   LDLNV  AW  G TGKGVT  IMDDGIDYLHPDL+ NYNAE+SYDFSSNDPYP+PRYTDDWFNSHGTRCAGE+SA  +N ICGVGVAYNSK+AG+RMLDQP+MTD+IEA+++S+    IDIYSASWGPTD+G+TVDGPR  T++A+ +GVNKGR GKGSIYVWASGDGG+ DDCNCDGYA+SMWTISINSA NDG TA YDESCSSTLASTFSNG+   + +AGV T DLYG CTL HSGTSAAAPEAAGVFALALEAN  + WRDMQHLTVLTSK       D  H W  NG GLEFNHLFGYGVLDAG MV++AK W  VPERFHC+ G +    +   T  L+L + TDAC+      V YLEHVQA I+V A+RRGD+ + +TSPMGT S++LS RP+DDDS  GF KWPFMTTHTWGE+ RG W L + F    P  +G+  EW L+LHGTQ+ PY
Sbjct:   15 FLFCVMVFASAERPVFTNHFLVELH-KGGEDKARQVAAEHGFGV-RKLPFAEGLYHFYHNGLAKAKRRRSLHHKQQLERDPRVKMALQQEGFDRKKRGYRDINE----------------------IDINM---NDPLFTKQWYLINTGQADGTPGLDLNVAEAWELGYTGKGVTIGIMDDGIDYLHPDLASNYNAEASYDFSSNDPYPYPRYTDDWFNSHGTRCAGEVSAAANNNICGVGVAYNSKVAGIRMLDQPFMTDIIEASSISHMPQLIDIYSASWGPTDNGKTVDGPRELTLQAMADGVNKGRGGKGSIYVWASGDGGSYDDCNCDGYASSMWTISINSAINDGRTALYDESCSSTLASTFSNGRK-RNPEAGVATTDLYGNCTLRHSGTSAAAPEAAGVFALALEANLGLTWRDMQHLTVLTSK--RNQLHDEVHQWRRNGVGLEFNHLFGYGVLDAGAMVKMAKDWKTVPERFHCVGGSVQDPEKIPSTGKLVLTLTTDACEGKENF-VRYLEHVQAVITVNATRRGDLNINMTSPMGTKSILLSRRPRDDDSKVGFDKWPFMTTHTWGEDARGTWTLELGFVGSAP-QKGVLKEWTLMLHGTQSAPY 599

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BLAST of pc2 vs. uniprot
Match: gi|75061998|sp|Q5REC2|NEC2_PONAB (RecName: Full=Neuroendocrine convertase 2; Short=NEC 2; AltName: Full=Prohormone convertase 2; AltName: Full=Proprotein convertase 2; Short=PC2; Flags: Precursor)

HSP 1 Score: 686.411 bits (1770), Expect = 0.000e+0
Identity = 370/617 (59.97%), Postives = 438/617 (70.99%), Query Frame = 2

Query:   98 LLFLIQIYTIYGK-IVTNQWHVRLHDPGTHDLANKVAQETGFSLLRNHIQSPNEFVYHHKAVPHVSSIPSWNHHKVLLSHPLVKEAKQVEGFIRKKRGFKPIKKQDRIPLPTINKKGIPGRGKTENIKENMKLPTDPLFSKEWYIRNTGQADGVKDLDLNVLSAWAQGITGKGVTTAIMDDGIDYLHPDLSKNYNAESSYDFSSNDPYPFPRYTDDWFNSHGTRCAGEISAERDNGICGVGVAYNSKIAGLRMLDQPYMTDLIEAAAMSYDRDNIDIYSASWGPTDDGRTVDGPRNETMRAIVEGVNKGRKGKGSIYVWASXXXXXXXXXXXXXXXXSMWTISINSATNDGETASYDESCSSTLASTFSNGKAWFSLDAGVGTVDLYGQCTLHHSGTSAAAPEAAGVFALALEANSNIGWRDMQHLTVLTSKXXXXXXXXXXXXWTINGAGLEFNHLFGYGVLDAGDMVRVAKKWVNVPERFHCIAGQINKRYRFNVTKALILEIDTDACKSDTGHRVNYLEHVQAFISVKASRRGDITMFLTSPMGTTSMILSHRPKDDDSTRGFTKWPFMTTHTWGENPRGKWRLTIMFDTKDPLSQGIFSEWVLVLHGTQNRPY 1945
             LF + ++    + + TN + V LH  G  D A +VA E GF + R    +   + ++H  +       S +H + L   P VK A Q EGF RKKRG++ I +                      I  NM    DPLF+K+WY+ NTGQADG   LDLNV  AW  G TGKGVT  IMDDGIDYLHPDL+ NYNAE+SYDFSSNDPYP+PRYTDDWFNSHGTRCAGE+SA  +N ICGVGVAYNSK+AG+RMLDQP+MTD+IEA+++S+    IDIYSASWGPTD+G+TVDGPR  T++A+ +GVNKGR GKGSIYVWASGDGG+ DDCNCDGYA+SMWTISINSA NDG TA YDESCSSTLASTFSNG+   + +AGV T DLYG CTL HSGTSAAAPEAAGVFALALEAN  + WRDMQHLTVLTSK       D  H W  NG GLEFNHLFGYGVLDAG MV++AK W  VPERFHC+ G +    +   T  L+L + TDAC+      V YLEHVQA I+V A+RRGD+ + +TSPMGT S++LS RP+DDDS  GF KWPFMTTHTWGE+ RG W L + F    P  +G+  EW L+LHGTQ+ PY
Sbjct:   15 FLFCVMVFASAERPVFTNHFLVELH-KGGEDEARQVAAEHGFGV-RKLPFAEGLYHFYHNGLAKAKRRRSLHHKQQLERDPRVKMALQQEGFDRKKRGYRDINE----------------------IDINM---NDPLFTKQWYLINTGQADGTPGLDLNVAEAWELGYTGKGVTIGIMDDGIDYLHPDLASNYNAEASYDFSSNDPYPYPRYTDDWFNSHGTRCAGEVSAAANNNICGVGVAYNSKVAGIRMLDQPFMTDIIEASSISHMPQLIDIYSASWGPTDNGKTVDGPRELTLQAMADGVNKGRGGKGSIYVWASGDGGSYDDCNCDGYASSMWTISINSAINDGRTALYDESCSSTLASTFSNGRK-RNPEAGVATTDLYGNCTLRHSGTSAAAPEAAGVFALALEANLGLTWRDMQHLTVLTSK--RNQLHDEVHQWRRNGVGLEFNHLFGYGVLDAGAMVKMAKDWKTVPERFHCVGGSVQDPEKIPSTGKLVLTLTTDACEGKENF-VRYLEHVQAVITVNATRRGDLNINMTSPMGTKSILLSRRPRDDDSKVGFDKWPFMTTHTWGEDARGTWTLELGFVGSAP-QKGVLKEWTLMLHGTQSAPY 599

[Close]

BLAST of pc2 vs. uniprot
Match: gi|128004|sp|P28841|NEC2_RAT (RecName: Full=Neuroendocrine convertase 2; Short=NEC 2; AltName: Full=KEX2-like endoprotease 2; AltName: Full=Prohormone convertase 2; AltName: Full=Proprotein convertase 2; Short=PC2; Flags: Precursor)

HSP 1 Score: 684.871 bits (1766), Expect = 0.000e+0
Identity = 370/645 (57.36%), Postives = 448/645 (69.46%), Query Frame = 2

Query:   98 LLFLIQIYTIYGK-IVTNQWHVRLHDPGTHDLANKVAQETGFSLLRNHIQSPNEFVYHHKAVPHVSSIPSWNHHKVLLSHPLVKEAKQVEGFIRKKRGFKPIKKQDRIPLPTINKKGIPGRGKTENIKENMKLPTDPLFSKEWYIRNTGQADGVKDLDLNVLSAWAQGITGKGVTTAIMDDGIDYLHPDLSKNYNAESSYDFSSNDPYPFPRYTDDWFNSHGTRCAGEISAERDNGICGVGVAYNSKIAGLRMLDQPYMTDLIEAAAMSYDRDNIDIYSASWGPTDDGRTVDGPRNETMRAIVEGVNKGRKGKGSIYVWASXXXXXXXXXXXXXXXXSMWTISINSATNDGETASYDESCSSTLASTFSNGKAWFSLDAGVGTVDLYGQCTLHHSGTSAAAPEAAGVFALALEANSNIGWRDMQHLTVLTSKXXXXXXXXXXXXWTINGAGLEFNHLFGYGVLDAGDMVRVAKKWVNVPERFHCIAGQINKRYRFNVTKALILEIDTDACKSDTGHRVNYLEHVQAFISVKASRRGDITMFLTSPMGTTSMILSHRPKDDDSTRGFTKWPFMTTHTWGENPRGKWRLTIMFDTKDPLSQGIFSEWVLVLHGTQNRPYDKLSSSLEKIIPKLGVVKRQHASNRFSQ 2029
            LLF + ++    + + TN + V LH  G  + A +VA E GF + R    +   + ++H  +       S +H + L   P +K A Q EGF RKKRG++ I +                      I  NM    DPLF+K+WY+ NTGQADG   LDLNV  AW  G TGKGVT  IMDDGIDYLHPDL+ NYN+++SYDFSSNDPYP+PRYTDDWFNSHGTRCAGE+SA   N ICGVGVAYNSK+AG+RMLDQP+MTD+IEA+++S+    IDIYSASWGPTD+G+TVDGPR  T++A+ +GVNKGR GKGSIYVWASGDGG+ DDCNCDGYA+SMWTISINSA NDG TA YDESCSSTLASTFSNG+   + +AGV T DLYG CTL HSGTSAAAPEAAGVFALALEAN ++ WRDMQHLTVLTSK       D  H W  NG GLEFNHLFGYGVLDAG MV++AK W  VPERFHC+ G +    +   T  L+L + T+AC+      V YLEHVQA I+V A+RRGD+ + +TSPMGT S++LS RP+DDDS  GF KWPFMTTHTWGE+ RG W L + F    P  +G+  EW L+LHGTQ+ PY  +   +     KL + K+Q       +
Sbjct:   14 LLFCVMVFASAERPVFTNHFLVELHKDGEEE-ARQVAAEHGFGV-RKLPFAEGLYHFYHNGLAKAKRRRSLHHKRQLERDPRIKMALQQEGFDRKKRGYRDINE----------------------IDINM---NDPLFTKQWYLFNTGQADGTPGLDLNVAEAWELGYTGKGVTIGIMDDGIDYLHPDLAYNYNSDASYDFSSNDPYPYPRYTDDWFNSHGTRCAGEVSAAASNNICGVGVAYNSKVAGIRMLDQPFMTDIIEASSISHMPQLIDIYSASWGPTDNGKTVDGPRELTLQAMADGVNKGRGGKGSIYVWASGDGGSYDDCNCDGYASSMWTISINSAINDGRTALYDESCSSTLASTFSNGRK-RNPEAGVATTDLYGNCTLRHSGTSAAAPEAAGVFALALEANVDLTWRDMQHLTVLTSK--RNQLHDEVHQWRRNGVGLEFNHLFGYGVLDAGAMVKMAKDWKTVPERFHCVGGSVQNPEKIPPTGKLVLTLQTNACEGKENF-VRYLEHVQAVITVNATRRGDLNINMTSPMGTKSILLSRRPRDDDSKVGFDKWPFMTTHTWGEDARGTWTLELGFVGSAP-QKGLLKEWTLMLHGTQSAPY--IDQVVRDYQSKLAMSKKQELEEELDE 624

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BLAST of pc2 vs. uniprot
Match: gi|128003|sp|P21661|NEC2_MOUSE (RecName: Full=Neuroendocrine convertase 2; Short=NEC 2; AltName: Full=KEX2-like endoprotease 2; AltName: Full=Prohormone convertase 2; AltName: Full=Proprotein convertase 2; Short=PC2; Flags: Precursor)

HSP 1 Score: 684.485 bits (1765), Expect = 0.000e+0
Identity = 370/645 (57.36%), Postives = 447/645 (69.30%), Query Frame = 2

Query:   98 LLFLIQIYTIYGK-IVTNQWHVRLHDPGTHDLANKVAQETGFSLLRNHIQSPNEFVYHHKAVPHVSSIPSWNHHKVLLSHPLVKEAKQVEGFIRKKRGFKPIKKQDRIPLPTINKKGIPGRGKTENIKENMKLPTDPLFSKEWYIRNTGQADGVKDLDLNVLSAWAQGITGKGVTTAIMDDGIDYLHPDLSKNYNAESSYDFSSNDPYPFPRYTDDWFNSHGTRCAGEISAERDNGICGVGVAYNSKIAGLRMLDQPYMTDLIEAAAMSYDRDNIDIYSASWGPTDDGRTVDGPRNETMRAIVEGVNKGRKGKGSIYVWASXXXXXXXXXXXXXXXXSMWTISINSATNDGETASYDESCSSTLASTFSNGKAWFSLDAGVGTVDLYGQCTLHHSGTSAAAPEAAGVFALALEANSNIGWRDMQHLTVLTSKXXXXXXXXXXXXWTINGAGLEFNHLFGYGVLDAGDMVRVAKKWVNVPERFHCIAGQINKRYRFNVTKALILEIDTDACKSDTGHRVNYLEHVQAFISVKASRRGDITMFLTSPMGTTSMILSHRPKDDDSTRGFTKWPFMTTHTWGENPRGKWRLTIMFDTKDPLSQGIFSEWVLVLHGTQNRPYDKLSSSLEKIIPKLGVVKRQHASNRFSQ 2029
             LF + ++    + + TN + V LH  G  + A +VA E GF + R    +   + ++H  +       S +H + L   P +K A Q EGF RKKRG++ I +                      I  NM    DPLF+K+WY+ NTGQADG   LDLNV  AW  G TGKGVT  IMDDGIDYLHPDL+ NYNA++SYDFSSNDPYP+PRYTDDWFNSHGTRCAGE+SA   N ICGVGVAYNSK+AG+RMLDQP+MTD+IEA+++S+    IDIYSASWGPTD+G+TVDGPR  T++A+ +GVNKGR GKGSIYVWASGDGG+ DDCNCDGYA+SMWTISINSA NDG TA YDESCSSTLASTFSNG+   + +AGV T DLYG CTL HSGTSAAAPEAAGVFALALEAN ++ WRDMQHLTVLTSK       D  H W  NG GLEFNHLFGYGVLDAG MV++AK W  VPERFHC+ G +    +   T  L+L + T+AC+      V YLEHVQA I+V A+RRGD+ + +TSPMGT S++LS RP+DDDS  GF KWPFMTTHTWGE+ RG W L + F    P  +G+  EW L+LHGTQ+ PY  +   +     KL + K+Q       +
Sbjct:   14 FLFCVMVFASAERPVFTNHFLVELHKDGEEE-ARQVAAEHGFGV-RKLPFAEGLYHFYHNGLAKAKRRRSLHHKRQLERDPRIKMALQQEGFDRKKRGYRDINE----------------------IDINM---NDPLFTKQWYLFNTGQADGTPGLDLNVAEAWELGYTGKGVTIGIMDDGIDYLHPDLAYNYNADASYDFSSNDPYPYPRYTDDWFNSHGTRCAGEVSAAASNNICGVGVAYNSKVAGIRMLDQPFMTDIIEASSISHMPQLIDIYSASWGPTDNGKTVDGPRELTLQAMADGVNKGRGGKGSIYVWASGDGGSYDDCNCDGYASSMWTISINSAINDGRTALYDESCSSTLASTFSNGRK-RNPEAGVATTDLYGNCTLRHSGTSAAAPEAAGVFALALEANLDLTWRDMQHLTVLTSK--RNQLHDEVHQWRRNGVGLEFNHLFGYGVLDAGAMVKMAKDWKTVPERFHCVGGSVQNPEKIPPTGKLVLTLKTNACEGKENF-VRYLEHVQAVITVNATRRGDLNINMTSPMGTKSILLSRRPRDDDSKVGFDKWPFMTTHTWGEDARGTWTLELGFVGSAP-QKGLLKEWTLMLHGTQSAPY--IDQVVRDYQSKLAMSKKQELEEELDE 624

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BLAST of pc2 vs. uniprot
Match: gi|417351|sp|Q03333|NEC2_PIG (RecName: Full=Neuroendocrine convertase 2; Short=NEC 2; AltName: Full=KEX2-like endoprotease 2; AltName: Full=Prohormone convertase 2; AltName: Full=Proprotein convertase 2; Short=PC2; Flags: Precursor)

HSP 1 Score: 682.174 bits (1759), Expect = 0.000e+0
Identity = 368/617 (59.64%), Postives = 438/617 (70.99%), Query Frame = 2

Query:   98 LLFLIQIYTIYGK-IVTNQWHVRLHDPGTHDLANKVAQETGFSLLRNHIQSPNEFVYHHKAVPHVSSIPSWNHHKVLLSHPLVKEAKQVEGFIRKKRGFKPIKKQDRIPLPTINKKGIPGRGKTENIKENMKLPTDPLFSKEWYIRNTGQADGVKDLDLNVLSAWAQGITGKGVTTAIMDDGIDYLHPDLSKNYNAESSYDFSSNDPYPFPRYTDDWFNSHGTRCAGEISAERDNGICGVGVAYNSKIAGLRMLDQPYMTDLIEAAAMSYDRDNIDIYSASWGPTDDGRTVDGPRNETMRAIVEGVNKGRKGKGSIYVWASXXXXXXXXXXXXXXXXSMWTISINSATNDGETASYDESCSSTLASTFSNGKAWFSLDAGVGTVDLYGQCTLHHSGTSAAAPEAAGVFALALEANSNIGWRDMQHLTVLTSKXXXXXXXXXXXXWTINGAGLEFNHLFGYGVLDAGDMVRVAKKWVNVPERFHCIAGQINKRYRFNVTKALILEIDTDACKSDTGHRVNYLEHVQAFISVKASRRGDITMFLTSPMGTTSMILSHRPKDDDSTRGFTKWPFMTTHTWGENPRGKWRLTIMFDTKDPLSQGIFSEWVLVLHGTQNRPY 1945
            LLF + ++    + + TN + V LH  G  + A +VA E GF + R    +   + ++H  +       S +H + L   P VK A Q EGF RKKRG++ I +                      I  NM    DPLF+K+WY+ NTGQADG   LDLNV  AW  G TGKGVT  IMDDGIDYLHPDL+ NYNAE+SYDFSSNDPYP+PRYTDDWFNSHGTRCAGE+SA  +N ICGVGVAY+SK+AG+RMLDQP+MTD+IEA+++S+    IDIYSASWGPTD+G+TVDGPR  T++A+ +GVNKGR GKGSIYVWASGDGG+ DDCNCDGYA+SMWTISINSA NDG TA YDESCSSTLASTFSNG+   + +AGV T DLYG CTL HSGTSAAAPEAAGVFALALEAN  + WRDMQHLTVLTSK       D  H W  NG GLEFNHLFGYGVLDAG MV++AK W  VPERFHC+ G +    +   T  L+L + TDAC+      V YLEHVQA I+V A+RRGD+ + +TSPMGT S++LS RP+DDDS  GF KWPFMTTHTWGE+ RG W L + F    P  +G   EW L+LHG+Q+ PY
Sbjct:   15 LLFCVTVFASAERPVFTNHFLVELHKGGEEE-ARQVAAEHGFGV-RKLPFAEGLYHFYHNGLAKAKRRRSLHHKQRLERDPRVKRALQQEGFDRKKRGYRDINE----------------------IDINM---NDPLFTKQWYLINTGQADGTPGLDLNVAEAWELGYTGKGVTIGIMDDGIDYLHPDLASNYNAEASYDFSSNDPYPYPRYTDDWFNSHGTRCAGEVSAAANNNICGVGVAYSSKVAGIRMLDQPFMTDIIEASSISHMPQLIDIYSASWGPTDNGKTVDGPRELTLQAMADGVNKGRGGKGSIYVWASGDGGSYDDCNCDGYASSMWTISINSAINDGRTALYDESCSSTLASTFSNGRK-RNPEAGVATTDLYGNCTLRHSGTSAAAPEAAGVFALALEANLGLTWRDMQHLTVLTSK--RNQLHDEVHQWRRNGVGLEFNHLFGYGVLDAGAMVKMAKDWKTVPERFHCVGGSVQDPEKIPSTGKLVLTLTTDACEGKENF-VRYLEHVQAVITVNATRRGDLNINMTSPMGTKSILLSRRPRDDDSKVGFDKWPFMTTHTWGEDARGTWTLELGFVGSAP-QKGAVKEWTLMLHGSQSAPY 599

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BLAST of pc2 vs. RefSeq Drosophila melanogaster
Match: gi|17136192|ref|NP_477318.1| (amontillado [Drosophila melanogaster])

HSP 1 Score: 701.819 bits (1810), Expect = 0.000e+0
Identity = 383/631 (60.70%), Postives = 452/631 (71.63%), Query Frame = 2

Query:  137 IVTNQWHVRLHDPGTHDLANKVAQETGFSLLRNHIQSP-NEFVYHHKAVPHVSSIPSWNHHKVLLSHPLVKEAKQVEGFIRKKRGFKPIKKQDRIPLPTINKKGIPGR-GKTENIKENMKLPTDPLFSKEWYIRNTGQADGVKDLDLNVLSAWAQGITGKGVTTAIMDDGIDYLHPDLSKNYNAESSYDFSSNDPYPFPRYTDDWFNSHGTRCAGEISAERDNGICGVGVAYNSKIAGLRMLDQPYMTDLIEAAAMSYDRDNIDIYSASWGPTDDGRTVDGPRNETMRAIVEGVNKGRKGKGSIYVWASXXXXXXXXXXXXXXXXSMWTISINSATNDGETASYDESCSSTLASTFSNGKAWFSLDAGVGTVDLYGQCTLHHSGTSAAAPEAAGVFALALEANSNIGWRDMQHLTVLTSKXXXXXXXXXXXXWTINGAGLEFNHLFGYGVLDAGDMVRVAKKWVNVPERFHCIAGQINKRYRFNVTKALILEIDTDACKSDTGHRVNYLEHVQAFISVKASRRGDITMFLTSPMGTTSMILSHRPKDDDSTRGFTKWPFMTTHTWGENPRGKWRLTIMFDTKDPLSQGIFSEWVLVLHGTQNRPYDKLSSSLEKIIPKLGVVKRQHASNRF 2023
            + T+ + VR      +  A+ VA + GF  L   + +  +E+ + H+ +PH  S  S  H + L SHP V  A Q  GF R KRG +P        +P I+      + G+   I E    PTDP F  +WY++NTGQ  G   LDLNV +AWAQGITGK VTTAIMDDG+DY+HPDL  NYNAE+SYDFSSNDP+P+PRYTDDWFNSHGTRCAGE++A RDNGICGVGVAY+SKIAG+RMLDQPYMTDLIEA +M ++   I IYSASWGPTDDG+TVDGPRN TMRAIV+GVN+GR G G+IYVWASGDGG  DDCNCDGYAASMWTISINSA NDG+ A YDESCSSTLASTFSNG      + GV T DLYG+CT  HSGTSAAAPEAAGVFALALEAN  + WRD+QHLTVLTSKRN L D   R +WT+NG GLEFNHLFG+GVLDAG MV ++K+W +VP R+HC AG++ +     + ++L  EI TDACK  T   VNYLEHVQA IS  ASRRGD+ +FLTSPMGT SMILS R  DDD   GFTKWPFMTTH+WGE P+G W+L   F++      G   EW LVLHGT+  PY  L  S      KL +VK+ H   + 
Sbjct:   39 VFTSSFLVRFRRGVDNSFAHDVADKYGFDNLGPLVGADGHEYHFKHRTLPHARSRRSLTHTRALKSHPAVHTAVQQPGFKRVKRGLRPA-------VPAIHGMKFDLKVGEGNRIDEE---PTDPYFPMQWYLKNTGQNGGKVRLDLNVQAAWAQGITGKNVTTAIMDDGVDYMHPDLKFNYNAEASYDFSSNDPFPYPRYTDDWFNSHGTRCAGEVAAARDNGICGVGVAYDSKIAGIRMLDQPYMTDLIEANSMGHEPHKIHIYSASWGPTDDGKTVDGPRNATMRAIVQGVNEGRNGLGNIYVWASGDGGEEDDCNCDGYAASMWTISINSAINDGQNAHYDESCSSTLASTFSNGAK--DPNTGVATTDLYGKCTTTHSGTSAAAPEAAGVFALALEANPQLTWRDIQHLTVLTSKRNSLFDAKNRFHWTMNGVGLEFNHLFGFGVLDAGAMVTLSKQWHSVPPRYHCEAGELTQPQAIVMGRSLFWEIKTDACKG-TDTEVNYLEHVQAVISANASRRGDLELFLTSPMGTKSMILSRRANDDDHRDGFTKWPFMTTHSWGEYPQGTWKLEARFNSPQ-TRHGNLLEWSLVLHGTKEAPYRTLHPSSPH--SKLAIVKKAHEDKKM 653

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BLAST of pc2 vs. RefSeq Drosophila melanogaster
Match: gi|281360987|ref|NP_001162774.1| (furin 2, isoform I [Drosophila melanogaster])

HSP 1 Score: 428.328 bits (1100), Expect = 7.879e-131
Identity = 270/628 (42.99%), Postives = 380/628 (60.51%), Query Frame = 2

Query:  137 IVTNQWHVRLHDPGTHDLANKVAQETGFSLLRNHIQS-PNEFVYHHKAVPHVSSIPSWNHHKVLLSHPLVKEAKQVEGFIRKKRGFKPIKKQDRIPLPTINKKGIPGRGKTENIKENMKLPTDPLFSKEWYIRNTGQADGVKDLDLNVLSAWAQGITGKGVTTAIMDDGIDYLHPDLSKNYNAESSYDFSSNDPYPFPRYTDDWFNSHGTRCAGEISAERDNGICGVGVAYNSKIAGLRMLDQPYMTDLIEAAAMSYDRDNIDIYSASWGPTDDGRTVDGPRNETMRAIVEGVNKGRKGKGSIYVWASXXXXX-XXXXXXXXXXXSMWTISINSATNDGETASYDESCSSTLASTFSNGKAWFSLDAGVGTVDLYGQ------CTLHHSGTSAAAPEAAGVFALALEANSNIGWRDMQHLTVLTSKXXXXXXXXXXXXWTINGAGLEFNHLFGYGVLDAGDMVRVAKKWVNVPERFHCIAGQINKRYRFN--VTKALILEIDTDACKSDTGHRVNYLEHVQAFISVKASRRGDITMFLTSPMGTTSMILSHRPKDDDSTRGFTKWPFMTTHTWGENPRGKWRLTIMFDTKDPLSQ-GIFSEWVLVLHGTQNRPYDKLSSSLEKIIPKL 1987
            I TN++ V +  P    +A+ +A + GF + R  I S  N +++ H  V   S   S  H   L S   VK  +Q    +R+KR       QD     +I+      R +  ++  +   P DPLF ++WY+ N G  DG   LD+NV  AW +G TGKGV  +I+DDGI   HPDL++NY+ E+S+D + ND  P P+  D+  N HGTRCAGE++A   N  CGVGVAYN+ I G+RMLD   + D++EA A+S +  +IDIYSASWGP DDG TVDGP     RA + GV  GR+GKGSI+VWASG+GG   D CNCDGY  S++T+SI+SAT  G    Y E CSSTLA+T+S+G      D  V TVD+ G       CT+ H+GTSA+AP AAG+ ALALEAN  + WRDMQ+L V TS+       ++ + WT+NG   +++H FGYG++DAG MV +A++W +VP +  C + + N+  + +      L   +D + C + T + V YLEHVQ  I+++   RG++ + LTSPMGTTS +L  RP+D   +  F  WPF++ H WGE   G+W L ++   +  ++Q GI S+W L+ +GT  +P  +L S L    P+L
Sbjct:  238 IYTNEFAVNI--PAGKQMADVIATKHGF-INRGQIGSLDNYYLFQHHHVSKRSLRSSRKHQGALKSENEVKWMQQQHEKVRRKRDGP---YQDLPTYKSISLASHSQRMEYRDVSSHFIFP-DPLFKEQWYL-NGGAKDG---LDMNVGPAWQKGYTGKGVVVSILDDGIQTNHPDLAQNYDPEASFDINGNDSDPTPQ--DNGDNKHGTRCAGEVAAVAFNNFCGVGVAYNASIGGVRMLDGK-VNDVVEAQALSLNPSHIDIYSASWGPEDDGSTVDGPGPLARRAFIYGVTSGRQGKGSIFVWASGNGGRYTDSCNCDGYTNSIFTLSISSATQAGFKPWYLEECSSTLATTYSSGTPGH--DKSVATVDMDGSLRPDHICTVEHTGTSASAPLAAGICALALEANPELTWRDMQYLVVYTSR---PAPLEKENGWTLNGVKRKYSHKFGYGLMDAGAMVSLAEQWTSVPPQHICKSRENNEDRKIDGAYGSTLSTHMDVNGC-AGTINEVRYLEHVQCRITLRFFPRGNLRILLTSPMGTTSTLLFERPRDIVKSN-FDDWPFLSVHFWGEKAEGRWTLQVINGGRRRVNQPGILSKWQLIFYGTSTQPM-RLKSELLNSSPQL 843

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BLAST of pc2 vs. RefSeq Drosophila melanogaster
Match: gi|24642484|ref|NP_727963.1| (furin 2, isoform A [Drosophila melanogaster])

HSP 1 Score: 420.624 bits (1080), Expect = 4.702e-128
Identity = 272/651 (41.78%), Postives = 387/651 (59.45%), Query Frame = 2

Query:  137 IVTNQWHVRLHDPGTHDLANKVAQETGFSLLRNHIQS-PNEFVYHHKAVPHVSSIPSWNHHKVLLSHPLVKEAKQVEGFIRKKRG--------FKP--IKKQ------DRIPLPTINKKGIP-----GRGKTENIKENMKLPTDPLFSKEWYI--RNTGQADGVKDLDLNVLSAWAQGITGKGVTTAIMDDGIDYLHPDLSKNYNAESSYDFSSNDPYPFPRYTDDWFNSHGTRCAGEISAERDNGICGVGVAYNSKIAGLRMLDQPYMTDLIEAAAMSYDRDNIDIYSASWGPTDDGRTVDGPRNETMRAIVEGVNKGRKGKGSIYVWASXXXXX-XXXXXXXXXXXSMWTISINSATNDGETASYDESCSSTLASTFSNGKAWFSLDAGVGTVDLYGQ------CTLHHSGTSAAAPEAAGVFALALEANSNIGWRDMQHLTVLTSKXXXXXXXXXXXXWTINGAGLEFNHLFGYGVLDAGDMVRVAKKWVNVPERFHCIAGQINKRYRFN--VTKALILEIDTDACKSDTGHRVNYLEHVQAFISVKASRRGDITMFLTSPMGTTSMILSHRPKDDDSTRGFTKWPFMTTHTWGENPRGKWRLTIMFDTKDPLSQ-GIFSEWVLVLHGTQNRPYDKLSSSLEKIIPKL 1987
            I TN++ V +  P    +A+ +A + GF + R  I S  N +++ H  V   S   S  H   L S   VK  +Q    +R+KR         + P  + +Q      D  P  + + + I       R +  ++  +   P DPLF ++WY+  +N G  DG   LD+NV  AW +G TGKGV  +I+DDGI   HPDL++NY+ E+S+D + ND  P P+  D+  N HGTRCAGE++A   N  CGVGVAYN+ I G+RMLD   + D++EA A+S +  +IDIYSASWGP DDG TVDGP     RA + GV  GR+GKGSI+VWASG+GG   D CNCDGY  S++T+SI+SAT  G    Y E CSSTLA+T+S+G      D  V TVD+ G       CT+ H+GTSA+AP AAG+ ALALEAN  + WRDMQ+L V TS+       ++ + WT+NG   +++H FGYG++DAG MV +A++W +VP +  C + + N+  + +      L   +D + C + T + V YLEHVQ  I+++   RG++ + LTSPMGTTS +L  RP+D   +  F  WPF++ H WGE   G+W L ++   +  ++Q GI S+W L+ +GT  +P  +L S L    P+L
Sbjct:  238 IYTNEFAVNI--PAGKQMADVIATKHGF-INRGQIGSLDNYYLFQHHHVSKRSLRSSRKHQGALKSENEVKWMQQQHEKVRRKRDGPYQDLPTYSPYNLLRQHGGYVVDPNPHLSFSPESISLASHSQRMEYRDVSSHFIFP-DPLFKEQWYLVSKNGGAKDG---LDMNVGPAWQKGYTGKGVVVSILDDGIQTNHPDLAQNYDPEASFDINGNDSDPTPQ--DNGDNKHGTRCAGEVAAVAFNNFCGVGVAYNASIGGVRMLDGK-VNDVVEAQALSLNPSHIDIYSASWGPEDDGSTVDGPGPLARRAFIYGVTSGRQGKGSIFVWASGNGGRYTDSCNCDGYTNSIFTLSISSATQAGFKPWYLEECSSTLATTYSSGTPGH--DKSVATVDMDGSLRPDHICTVEHTGTSASAPLAAGICALALEANPELTWRDMQYLVVYTSR---PAPLEKENGWTLNGVKRKYSHKFGYGLMDAGAMVSLAEQWTSVPPQHICKSRENNEDRKIDGAYGSTLSTHMDVNGC-AGTINEVRYLEHVQCRITLRFFPRGNLRILLTSPMGTTSTLLFERPRDIVKSN-FDDWPFLSVHFWGEKAEGRWTLQVINGGRRRVNQPGILSKWQLIFYGTSTQPM-RLKSELLNSSPQL 870

[Close]

BLAST of pc2 vs. RefSeq Drosophila melanogaster
Match: gi|24642486|ref|NP_727964.1| (furin 2, isoform B [Drosophila melanogaster])

HSP 1 Score: 420.624 bits (1080), Expect = 4.702e-128
Identity = 272/651 (41.78%), Postives = 387/651 (59.45%), Query Frame = 2

Query:  137 IVTNQWHVRLHDPGTHDLANKVAQETGFSLLRNHIQS-PNEFVYHHKAVPHVSSIPSWNHHKVLLSHPLVKEAKQVEGFIRKKRG--------FKP--IKKQ------DRIPLPTINKKGIP-----GRGKTENIKENMKLPTDPLFSKEWYI--RNTGQADGVKDLDLNVLSAWAQGITGKGVTTAIMDDGIDYLHPDLSKNYNAESSYDFSSNDPYPFPRYTDDWFNSHGTRCAGEISAERDNGICGVGVAYNSKIAGLRMLDQPYMTDLIEAAAMSYDRDNIDIYSASWGPTDDGRTVDGPRNETMRAIVEGVNKGRKGKGSIYVWASXXXXX-XXXXXXXXXXXSMWTISINSATNDGETASYDESCSSTLASTFSNGKAWFSLDAGVGTVDLYGQ------CTLHHSGTSAAAPEAAGVFALALEANSNIGWRDMQHLTVLTSKXXXXXXXXXXXXWTINGAGLEFNHLFGYGVLDAGDMVRVAKKWVNVPERFHCIAGQINKRYRFN--VTKALILEIDTDACKSDTGHRVNYLEHVQAFISVKASRRGDITMFLTSPMGTTSMILSHRPKDDDSTRGFTKWPFMTTHTWGENPRGKWRLTIMFDTKDPLSQ-GIFSEWVLVLHGTQNRPYDKLSSSLEKIIPKL 1987
            I TN++ V +  P    +A+ +A + GF + R  I S  N +++ H  V   S   S  H   L S   VK  +Q    +R+KR         + P  + +Q      D  P  + + + I       R +  ++  +   P DPLF ++WY+  +N G  DG   LD+NV  AW +G TGKGV  +I+DDGI   HPDL++NY+ E+S+D + ND  P P+  D+  N HGTRCAGE++A   N  CGVGVAYN+ I G+RMLD   + D++EA A+S +  +IDIYSASWGP DDG TVDGP     RA + GV  GR+GKGSI+VWASG+GG   D CNCDGY  S++T+SI+SAT  G    Y E CSSTLA+T+S+G      D  V TVD+ G       CT+ H+GTSA+AP AAG+ ALALEAN  + WRDMQ+L V TS+       ++ + WT+NG   +++H FGYG++DAG MV +A++W +VP +  C + + N+  + +      L   +D + C + T + V YLEHVQ  I+++   RG++ + LTSPMGTTS +L  RP+D   +  F  WPF++ H WGE   G+W L ++   +  ++Q GI S+W L+ +GT  +P  +L S L    P+L
Sbjct:  238 IYTNEFAVNI--PAGKQMADVIATKHGF-INRGQIGSLDNYYLFQHHHVSKRSLRSSRKHQGALKSENEVKWMQQQHEKVRRKRDGPYQDLPTYSPYNLLRQHGGYVVDPNPHLSFSPESISLASHSQRMEYRDVSSHFIFP-DPLFKEQWYLVSKNGGAKDG---LDMNVGPAWQKGYTGKGVVVSILDDGIQTNHPDLAQNYDPEASFDINGNDSDPTPQ--DNGDNKHGTRCAGEVAAVAFNNFCGVGVAYNASIGGVRMLDGK-VNDVVEAQALSLNPSHIDIYSASWGPEDDGSTVDGPGPLARRAFIYGVTSGRQGKGSIFVWASGNGGRYTDSCNCDGYTNSIFTLSISSATQAGFKPWYLEECSSTLATTYSSGTPGH--DKSVATVDMDGSLRPDHICTVEHTGTSASAPLAAGICALALEANPELTWRDMQYLVVYTSR---PAPLEKENGWTLNGVKRKYSHKFGYGLMDAGAMVSLAEQWTSVPPQHICKSRENNEDRKIDGAYGSTLSTHMDVNGC-AGTINEVRYLEHVQCRITLRFFPRGNLRILLTSPMGTTSTLLFERPRDIVKSN-FDDWPFLSVHFWGEKAEGRWTLQVINGGRRRVNQPGILSKWQLIFYGTSTQPM-RLKSELLNSSPQL 870

[Close]

BLAST of pc2 vs. RefSeq Drosophila melanogaster
Match: gi|24642488|ref|NP_727965.1| (furin 2, isoform C [Drosophila melanogaster])

HSP 1 Score: 420.624 bits (1080), Expect = 4.702e-128
Identity = 272/651 (41.78%), Postives = 387/651 (59.45%), Query Frame = 2

Query:  137 IVTNQWHVRLHDPGTHDLANKVAQETGFSLLRNHIQS-PNEFVYHHKAVPHVSSIPSWNHHKVLLSHPLVKEAKQVEGFIRKKRG--------FKP--IKKQ------DRIPLPTINKKGIP-----GRGKTENIKENMKLPTDPLFSKEWYI--RNTGQADGVKDLDLNVLSAWAQGITGKGVTTAIMDDGIDYLHPDLSKNYNAESSYDFSSNDPYPFPRYTDDWFNSHGTRCAGEISAERDNGICGVGVAYNSKIAGLRMLDQPYMTDLIEAAAMSYDRDNIDIYSASWGPTDDGRTVDGPRNETMRAIVEGVNKGRKGKGSIYVWASXXXXX-XXXXXXXXXXXSMWTISINSATNDGETASYDESCSSTLASTFSNGKAWFSLDAGVGTVDLYGQ------CTLHHSGTSAAAPEAAGVFALALEANSNIGWRDMQHLTVLTSKXXXXXXXXXXXXWTINGAGLEFNHLFGYGVLDAGDMVRVAKKWVNVPERFHCIAGQINKRYRFN--VTKALILEIDTDACKSDTGHRVNYLEHVQAFISVKASRRGDITMFLTSPMGTTSMILSHRPKDDDSTRGFTKWPFMTTHTWGENPRGKWRLTIMFDTKDPLSQ-GIFSEWVLVLHGTQNRPYDKLSSSLEKIIPKL 1987
            I TN++ V +  P    +A+ +A + GF + R  I S  N +++ H  V   S   S  H   L S   VK  +Q    +R+KR         + P  + +Q      D  P  + + + I       R +  ++  +   P DPLF ++WY+  +N G  DG   LD+NV  AW +G TGKGV  +I+DDGI   HPDL++NY+ E+S+D + ND  P P+  D+  N HGTRCAGE++A   N  CGVGVAYN+ I G+RMLD   + D++EA A+S +  +IDIYSASWGP DDG TVDGP     RA + GV  GR+GKGSI+VWASG+GG   D CNCDGY  S++T+SI+SAT  G    Y E CSSTLA+T+S+G      D  V TVD+ G       CT+ H+GTSA+AP AAG+ ALALEAN  + WRDMQ+L V TS+       ++ + WT+NG   +++H FGYG++DAG MV +A++W +VP +  C + + N+  + +      L   +D + C + T + V YLEHVQ  I+++   RG++ + LTSPMGTTS +L  RP+D   +  F  WPF++ H WGE   G+W L ++   +  ++Q GI S+W L+ +GT  +P  +L S L    P+L
Sbjct:  238 IYTNEFAVNI--PAGKQMADVIATKHGF-INRGQIGSLDNYYLFQHHHVSKRSLRSSRKHQGALKSENEVKWMQQQHEKVRRKRDGPYQDLPTYSPYNLLRQHGGYVVDPNPHLSFSPESISLASHSQRMEYRDVSSHFIFP-DPLFKEQWYLVSKNGGAKDG---LDMNVGPAWQKGYTGKGVVVSILDDGIQTNHPDLAQNYDPEASFDINGNDSDPTPQ--DNGDNKHGTRCAGEVAAVAFNNFCGVGVAYNASIGGVRMLDGK-VNDVVEAQALSLNPSHIDIYSASWGPEDDGSTVDGPGPLARRAFIYGVTSGRQGKGSIFVWASGNGGRYTDSCNCDGYTNSIFTLSISSATQAGFKPWYLEECSSTLATTYSSGTPGH--DKSVATVDMDGSLRPDHICTVEHTGTSASAPLAAGICALALEANPELTWRDMQYLVVYTSR---PAPLEKENGWTLNGVKRKYSHKFGYGLMDAGAMVSLAEQWTSVPPQHICKSRENNEDRKIDGAYGSTLSTHMDVNGC-AGTINEVRYLEHVQCRITLRFFPRGNLRILLTSPMGTTSTLLFERPRDIVKSN-FDDWPFLSVHFWGEKAEGRWTLQVINGGRRRVNQPGILSKWQLIFYGTSTQPM-RLKSELLNSSPQL 870

[Close]

BLAST of pc2 vs. Smed Unigenes AA
Match: SMU15019018 (SmedSxldir_c108536_g2_i2|m.79117|m.1373)

HSP 1 Score: 1197.96 bits (3098), Expect = 0.000e+0
Identity = 603/645 (93.49%), Postives = 628/645 (97.36%), Query Frame = 2

Query:   98 LLFLIQIYTIYGKIVTNQWHVRLHDPGTHDLANKVAQETGFSLLRNHIQSPNEFVYHHKAVPHVSSIPSWNHHKVLLSHPLVKEAKQVEGFIRKKRGFKPIKKQDRIPLPTINKKGIPGRGKTENIKENMKLPTDPLFSKEWYIRNTGQADGVKDLDLNVLSAWAQGITGKGVTTAIMDDGIDYLHPDLSKNYNAESSYDFSSNDPYPFPRYTDDWFNSHGTRCAGEISAERDNGICGVGVAYNSKIAGLRMLDQPYMTDLIEAAAMSYDRDNIDIYSASWGPTDDGRTVDGPRNETMRAIVEGVNKGRKGKGSIYVWASXXXXXXXXXXXXXXXXSMWTISINSATNDGETASYDESCSSTLASTFSNGKAWFSLDAGVGTVDLYGQCTLHHSGTSAAAPEAAGVFALALEANSNIGWRDMQHLTVLTSKXXXXXXXXXXXXWTINGAGLEFNHLFGYGVLDAGDMVRVAKKWVNVPERFHCIAGQINKRYRFNVTKALILEIDTDACKSDTGHRVNYLEHVQAFISVKASRRGDITMFLTSPMGTTSMILSHRPKDDDSTRGFTKWPFMTTHTWGENPRGKWRLTIMFDTKDPLSQGIFSEWVLVLHGTQNRPYDKLSSSLEKIIPKLGVVKRQHASNRFSQ* 2032
            LLFL + Y + GKIVTNQWHV LHDP T + ANKVAQETGFS+LRNH+ SPNEFV+HHK VPHVSS+PSW+ HKVLL+H LVK AKQVEGF+R+KRG+KPIKKQ R+PLPTINKKGIPG G+++NIK ++KLPTDPLFSKEWYIRNTGQADGVKDLDLNVLSAWAQGITGKGVTTAIMDDGIDYLHPDLSKNYNAESSYDFSSNDPYPFPRYTDDWFNSHGTRCAGEISAERDNGICGVGVAY+SKIAGLRMLDQPYMTDLIEAAAMSYDRDNIDIYSASWGPTDDGRTVDGPRNETMRAIVEGVNKGRKGKGSIYVWASGDGGAADDCNCDGYAASMWTISINSATNDGETASYDESCSSTLASTFSNGKAWFSLDAGVGTVDLYGQCTLHHSGTSAAAPEAAGVFALALEANSNIGWRDMQHLTVLTSKRNHLHDRDRRHNWTINGAGLEFNHLFGYGVLDAGDMVRVAKKWVNVPERFHCIAGQI+KRYRFNVTKALILEIDTDACKSD GHRVNYLEHVQAF+SVK+SRRGDITMFLTSPMGTTSMILSHRPKDDDSTRGFTKWPFMTTHTWGENPRGKW+LT+MFDTKDPLSQGIFSEWVLVLHGTQ+RPYDKLSSSLEKIIPKLGVVKRQHASNRFSQ*
Sbjct:    7 LLFLCE-YVVCGKIVTNQWHVHLHDPATQESANKVAQETGFSVLRNHLNSPNEFVFHHKTVPHVSSVPSWSQHKVLLAHHLVKNAKQVEGFLRRKRGYKPIKKQGRVPLPTINKKGIPGLGESDNIKVDLKLPTDPLFSKEWYIRNTGQADGVKDLDLNVLSAWAQGITGKGVTTAIMDDGIDYLHPDLSKNYNAESSYDFSSNDPYPFPRYTDDWFNSHGTRCAGEISAERDNGICGVGVAYDSKIAGLRMLDQPYMTDLIEAAAMSYDRDNIDIYSASWGPTDDGRTVDGPRNETMRAIVEGVNKGRKGKGSIYVWASGDGGAADDCNCDGYAASMWTISINSATNDGETASYDESCSSTLASTFSNGKAWFSLDAGVGTVDLYGQCTLHHSGTSAAAPEAAGVFALALEANSNIGWRDMQHLTVLTSKRNHLHDRDRRHNWTINGAGLEFNHLFGYGVLDAGDMVRVAKKWVNVPERFHCIAGQIDKRYRFNVTKALILEIDTDACKSDIGHRVNYLEHVQAFVSVKSSRRGDITMFLTSPMGTTSMILSHRPKDDDSTRGFTKWPFMTTHTWGENPRGKWKLTVMFDTKDPLSQGIFSEWVLVLHGTQSRPYDKLSSSLEKIIPKLGVVKRQHASNRFSQ* 650

[Close]

BLAST of pc2 vs. Smed Unigenes AA
Match: SMU15036165 (SmedSxlregen_c89995_g1_i1|m.42695|m.12874)

HSP 1 Score: 382.489 bits (981), Expect = 9.640e-122
Identity = 247/620 (39.84%), Postives = 349/620 (56.29%), Query Frame = 2

Query:  143 TNQWHVRLHDPGTHDLANKVAQETGFSLLRNHIQSPNEFVYHHKAVPHVSSIPSWNHHKVLLSHPLVKEAKQVEGFIRKKRGFKPIKKQDRIPLPTINKKGIPGRGKTENIKENMKLPTDPLFSKEWYIRNTGQADGVKDLDLNVLSAWAQGITGKGVTTAIMDDGIDYLHPDLSKNYNAESSYDFSSNDPYPFPRY-----TDDWFNSHGTRCAGEISAERDNGICGVGVAYNSKIAGLRMLDQPYMTDLIEAAAMSYDRDNIDIYSASWGPTDDGRTVDGPRNETMRAIVEGVNKGRKGKGSIYVWAS-XXXXXXXXXXXXXXXXSMWTISINSATNDGETASYDESCSSTLASTFSNGKAWFSLDA-GVGTVDLYGQCTLHHSGTSAAAPEAAGVFALALEANSNIGWRDMQHLTVLTSKXXXXXXXXXXXXWTINGAGLEFNHLFGYGVLDAGDMVRVAKKWVNVPERFHC--IAGQINKRYRFNVTKALILEIDTDACKSDTGHRVNYLEHVQAFISVKASRRGDITMFLTSPMGTTSMILSHRPKDDDSTRGFTKWPFMTTHTWGENPRGKWRLTIM-FDTKDPLSQGIFSEWVLVLHGTQNRPYDKLSSSLEK 1972
            T+ W V+++  GT D A  +A   GF  L N I  P+ + + H+ V   S  PS  +   L   P V   +Q    +R KR                                   +  DP + K WY+         K+  +N++SAW +G  G+ V  +I+DDGI+  HPDL +NY+  +SYD  SND  P PRY     T    N HGTRCAG+++A  +N ICGVGVAY + I G+RMLD   ++D +E+ ++     +IDIYSASWGP DDG+TVDGP      A  +G+ KGR G GSI+VWAS   G   D+CNCDGY  S++T+ +N+ +  G+   Y E CSSTLA T+S+G    S+D   + T D+  +CT  HSGTSA+AP AAG+ ALAL AN  + WRDMQHL V+T++        R  +W+ N AG E++H FG+G++DAG MV +A  W  VPE+  C  +A               +L I TDAC  ++  RV YLEHVQA IS+++++RG++ ++L SP  +TS +L+ R ++D ++ GF  WPFM+ H WGE   G W+LTI  +D +  L       W L+L+GT   P  + +S+  K
Sbjct:   27 TDTWAVQIN--GTVDDARILAATYGFVFL-NEIM-PSIYSFKHRRVSKRSIYPSNYYQSNLSDDPRVIWLEQQFAKVRVKR----------------------------------HIVNDPKWYKMWYLNKMN-----KENSMNIISAWKKGYRGQNVVVSILDDGIEKDHPDLKENYDPNASYDIISNDNNPEPRYISSNNTKIKDNHHGTRCAGQVAATANNRICGVGVAYKANIGGIRMLDGE-VSDSVESHSLRLFYQHIDIYSASWGPEDDGKTVDGPGELAKIAFEDGILKGRNGLGSIFVWASGNGGKNHDNCNCDGYTNSIFTLGVNAVSEIGDAPWYAEKCSSTLAVTYSSG----SMDERAIITTDVNHECTEQHSGTSASAPFAAGICALALSANRFLTWRDMQHLVVITAR----KANLRAVDWSTNAAGKEYSHSFGFGLMDAGAMVDLALNWTTVPEQHICHYVAPMQGGPISLKPYANEVLSITTDACSDNSKKRVRYLEHVQAKISLRSTKRGEVELWLISPSRSTSKLLTKR-RNDVASAGFHHWPFMSVHFWGEEAPGTWKLTIYSYDAEVTLIN-----WSLILYGTDTLPSHRQNSTHTK 588

[Close]

BLAST of pc2 vs. Smed Unigenes AA
Match: SMU15033125 (SmedSxlregen_c82367_g1_i3|m.22377|m.8734)

HSP 1 Score: 353.984 bits (907), Expect = 7.352e-106
Identity = 233/627 (37.16%), Postives = 345/627 (55.02%), Query Frame = 2

Query:  137 IVTNQWHVR-----------LHDPGTHDLANKVAQETGFSLLRNHIQSPNEF-VYHHKAVPHVSSIPSWNHHKVLLSHPLVKEAKQVEGFIRKKRGFKPIKKQDRIPLPTINKKGIPGRGKTENIKENMKLPTDPLFSKEWYIRNTGQADGVKDLDLNVLSAWAQGITGKGVTTAIMDDGIDYLHPDLSKNYNAESSYDFS--SNDPYPFPRYTDDWFNSHGTRCAGEISAERDNGICGVGVAYNSKIAGLRMLDQPYMTDLIEAAAMSYDRDNIDIYSASWGPTDDGRTVDGPRNETMRAIVEGVNKGRKGKGSIYVWASXXXXXXXXXXXXXXXXSMWTISINSATNDGETAS-YDESCSSTLASTFSNGKAWFSLDAGVGTVDLYGQCTLHHSGTSAAAPEAAGVFALALEANSNIGWRDMQHLTVLTSKXXXXXXXXXXXXWTINGAGLEFNHLFGYGVLDAGDMVRVAKKWVNVPERFHCIAGQINKRYRFNVTKALILEIDTDACKSDTGHRVNYLEHVQAFISVKASRRGDITMFLTSPMGTTSMILSHRPKDDDSTRG---FTKWPFMTTHTWGENPRGKWRLTI-MFDTKDPLSQGIFSEWVLVLHGTQNRPYDKLSS 1960
            I+ NQ+H             +  PG +  A  VA + GF +L++ ++  ++F V+ ++   + +S  S  H   L     V  A+Q     R KR F  IK+                          +K  +DPLF K+WY+  +      K +D+NV  AW  G TGKGVT +I+DDGIDY H DL +NY+ E+S+D +   NDP P  + T+   N HGTRCAGE+SA+ +N  CGVG+AYNS+I  +RMLD   +TD +EA A+S+ + +IDIYS SWGP D+G+ V+GP      A  +G+  GR G G+IYVWASG+GG   D       AS       S+ ++      Y ESC+STLAST+S+G  +   +  + + DL  +C   H+GTSA+AP AAG+ AL +EANSN+ WRD+Q++ VLTS            N+ +NGA  + ++L+G+G++D+G +VR+ + W  +P    C      K+        + L + TD C     ++VNY+EHV  ++ +   +RGD+ + L SP GT S IL +RP   D  RG   F  WP M+   WGE   G+W + I  + TK   S G++S + L ++GT+  P   +S+
Sbjct:   13 ILLNQFHFTFATKEHINEYVIQCPGGYSEAKTVAVQMGF-ILKHKMRGFDDFYVFKYR---YDNSENSKFHLHRLKRSVKVNWAEQQYKLTRVKRDFMKIKQ--------------------------IKF-SDPLFKKQWYLIRS--QFNTKLVDMNVKEAWELGYTGKGVTISILDDGIDYRHDDLKENYDPEASFDINGDDNDPLPNLKSTE---NRHGTRCAGEVSAKANNSKCGVGIAYNSRIGAVRMLDGD-VTDRVEAEALSFKQQHIDIYSGSWGPDDNGQKVEGPAILAKSAFKKGIRYGRNGLGNIYVWASGNGGKKSDSCACDGYASSIYTISISSVSENNRKPWYLESCASTLASTYSSGDGY---EQKIISTDLNNKCAFDHTGTSASAPLAAGIIALLIEANSNLTWRDVQYIIVLTSN----PHPFIDGNFIVNGANKKVSNLYGFGLMDSGKLVRIGRLWHKLPSHHFCKISYNGKKISLKDKFTVKLSVKTDGCPGK--NKVNYVEHVILYLKLDYDKRGDLRIILISPSGTRSEILPYRPH--DFARGPSTFDIWPLMSVQFWGEKASGEWSVEINNYGTKFSKSNGVWSNFELKIYGTEKWPIRLISA 591

[Close]

BLAST of pc2 vs. Smed Unigenes AA
Match: SMU15002657 (Asxlregen_comp67843_c0_seq3|m.34885|m.51170)

HSP 1 Score: 353.599 bits (906), Expect = 1.099e-105
Identity = 233/627 (37.16%), Postives = 345/627 (55.02%), Query Frame = 2

Query:  137 IVTNQWHVR-----------LHDPGTHDLANKVAQETGFSLLRNHIQSPNEF-VYHHKAVPHVSSIPSWNHHKVLLSHPLVKEAKQVEGFIRKKRGFKPIKKQDRIPLPTINKKGIPGRGKTENIKENMKLPTDPLFSKEWYIRNTGQADGVKDLDLNVLSAWAQGITGKGVTTAIMDDGIDYLHPDLSKNYNAESSYDFS--SNDPYPFPRYTDDWFNSHGTRCAGEISAERDNGICGVGVAYNSKIAGLRMLDQPYMTDLIEAAAMSYDRDNIDIYSASWGPTDDGRTVDGPRNETMRAIVEGVNKGRKGKGSIYVWASXXXXXXXXXXXXXXXXSMWTISINSATNDGETAS-YDESCSSTLASTFSNGKAWFSLDAGVGTVDLYGQCTLHHSGTSAAAPEAAGVFALALEANSNIGWRDMQHLTVLTSKXXXXXXXXXXXXWTINGAGLEFNHLFGYGVLDAGDMVRVAKKWVNVPERFHCIAGQINKRYRFNVTKALILEIDTDACKSDTGHRVNYLEHVQAFISVKASRRGDITMFLTSPMGTTSMILSHRPKDDDSTRG---FTKWPFMTTHTWGENPRGKWRLTI-MFDTKDPLSQGIFSEWVLVLHGTQNRPYDKLSS 1960
            I+ NQ+H             +  PG +  A  VA + GF +L++ ++  ++F V+ ++   + +S  S  H   L     V  A+Q     R KR F  IK+                          +K  +DPLF K+WY+  +      K +D+NV  AW  G TGKGVT +I+DDGIDY H DL +NY+ E+S+D +   NDP P  + T+   N HGTRCAGE+SA+ +N  CGVG+AYNS+I  +RMLD   +TD +EA A+S+ + +IDIYS SWGP D+G+ V+GP      A  +G+  GR G G+IYVWASG+GG   D       AS       S+ ++      Y ESC+STLAST+S+G  +   +  + + DL  +C   H+GTSA+AP AAG+ AL +EANSN+ WRD+Q++ VLTS            N+ +NGA  + ++L+G+G++D+G +VR+ + W  +P    C      K+        + L + TD C     ++VNY+EHV  ++ +   +RGD+ + L SP GT S IL +RP   D  RG   F  WP M+   WGE   G+W + I  + TK   S G++S + L ++GT+  P   +S+
Sbjct:   13 ILLNQFHFTFATKEHINEYVIQCPGGYSEAKTVAVQMGF-ILKHKMRGFDDFYVFKYR---YDNSENSKFHLHRLKRSVKVNWAEQQYKLTRVKRDFMKIKQ--------------------------IKF-SDPLFKKQWYLIRS--QFNTKLVDMNVKEAWELGYTGKGVTISILDDGIDYRHDDLKENYDPEASFDINGDDNDPLPNLKSTE---NRHGTRCAGEVSAKANNSKCGVGIAYNSRIGAVRMLDGD-VTDRVEAEALSFKQQHIDIYSGSWGPDDNGQKVEGPAILAKSAFKKGIRYGRNGLGNIYVWASGNGGKKSDSCACDGYASSIYTISISSVSENNRKPWYLESCASTLASTYSSGDGY---EQKIISTDLNNKCAFDHTGTSASAPLAAGIIALLIEANSNLTWRDVQYIIVLTSN----PHPFIDGNFIVNGANKKVSNLYGFGLMDSGKLVRIGRLWHKLPSHHFCKISYNGKKISLKDKFTVKLSVKTDGCPGK--NKVNYVEHVILYLKLDYDKRGDLRIILISPSGTRSEILPYRPH--DFARGPSTFDIWPLMSVQFWGEKASGEWSVEINNYGTKFSKSNGVWSNFELKIYGTEKWPIRLISA 591

[Close]

BLAST of pc2 vs. Smed Unigenes AA
Match: SMU15000885 (Asxlregen_comp60502_c0_seq1|m.9253|m.45850)

HSP 1 Score: 315.849 bits (808), Expect = 1.359e-96
Identity = 192/489 (39.26%), Postives = 280/489 (57.26%), Query Frame = 2

Query:  485 MKLPTDPLFSKEWYIRNTGQADGVKDLDLNVLSAWAQGITGKGVTTAIMDDGIDYLHPDLSKNYNAESSYDFSSNDPYPFPRYTDDWFNSHGTRCAGEISAERDNGICGVGVAYNSKIAGLRMLDQPYMTDLIEAAAMSYDRDNIDIYSASWGPTDDGRTVDGPRNETMRAIVEGVNKGRKGKGSIYVWAS-XXXXXXXXXXXXXXXXSMWTISINSATNDGETASYDESCSSTLASTFS-NGKAWFSLDAGVGTVDLYGQCTLHHSGTSAAAPEAAGVFALALEANSNIGWRDMQHLTVLTSKXXXXXXXXXXXXWTINGAGLEFNHLFGYGVLDAGDMVRVAKKWVNVPERFHCIAGQINKRYRFNVTKALILEIDTDACKSDTGHRVNYLEHVQAFISVKASRRGDITMFLTSPMGTTSMILSHRPKDDDSTRGFTKWPFMTTHTWGENPRGKWRLTIMFDTKDPLSQ-GIFSEWVLVLHGTQNRP 1942
            +++  DP +  EWY+ ++      K  D+ V   W   ITG+GV  AI+DDG+++ HPDL  NY+  SS D + ND  P P  T    N HGTRCA EI+   +N ICGVG+AYN KI G+RMLD P +  +IEA ++ ++ ++IDIYS+SWGP DDG+T++ P       +  G   GR GKG+I+VWAS   G   D C+CDGY +S++ IS+NS T+D +   + E C ST+ +T+S + ++ +SL A     D+ G+CT  HSGTSA+AP A+G+FAL LE N N+ WRD++HL   TS+    +       W  N AG   N  FG+G+L+A  MV+ A+ W NVP    C     + +   N   A I+    + CK     +V ++E +   +++    RG + + L SP G  + +L+ R   D S  G   WPF + H WGENP GKW + +     D   + G  ++  L  +GT+  P
Sbjct:  142 LEMFNDPKWPDEWYLFDSRFNSDQKSYDMRVTPVWYMNITGRGVKVAILDDGLEHTHPDLIDNYDPFSSTDLNDNDDDPSPDLTPGTSNEHGTRCASEIAMSANNKICGVGIAYNCKIGGIRMLDGP-VNGIIEAKSLGFNNNHIDIYSSSWGPLDDGKTMEQPSKLVQEVLRRGALSGRNGKGNIFVWASGNGGLYQDSCSCDGYVSSLYVISVNSITDDNKFPYFAEKCPSTMCATYSASSESKYSLIAA----DVKGKCTKKHSGTSASAPYASGIFALVLEMNPNLTWRDIKHLIAWTSE---YNWIKNNLGWKKNAAGFWVNEKFGFGLLNAYKMVKKAQNWKNVPPMTTCRVKVKSSKKISNKLPATIIAYG-NHCK----EKVAFIESIIILMNITYEVRGALLIKLQSPYGMNTTLLTTR-NLDKSKDGIINWPFHSVHNWGENPTGKWVVYVEDKINDDEDRSGEVTDCTLEFYGTKTTP 616

The following BLAST results are available for this feature:

BLAST of pc2 vs. RefSeq Human
BLAST of pc2 vs. uniprot
BLAST of pc2 vs. RefSeq Drosophila melanogaster
BLAST of pc2 vs. Smed Unigenes AA

BLAST of pc2 vs. RefSeq Human
Analysis Date: 2016-03-08 (Girardia Sp. BLASTX Human)
Total hits: 5


Match Name	E-value	Identity	Description
gi\|20336244\|ref\|NP_002585.2\|	0.000e+0	59.97	neuroendocrine convertase 2 isoform 1 preproprotei...	[more]
gi\|320118926\|ref\|NP_001188457.1\|	0.000e+0	61.03	neuroendocrine convertase 2 isoform 3 [Homo sapien...	[more]
gi\|320118928\|ref\|NP_001188458.1\|	0.000e+0	59.00	neuroendocrine convertase 2 isoform 2 preproprotei...	[more]
gi\|20336242\|ref\|NP_000430.3\|	1.796e-134	41.23	neuroendocrine convertase 1 isoform 1 preproprotei...	[more]
gi\|4505579\|ref\|NP_002560.1\|	4.086e-132	41.83	furin preproprotein [Homo sapiens]	[more]

BLAST of pc2 vs. uniprot
Analysis Date: 2016-03-08 (Girardia Sp. BLASTX Swissprot Uniprot)
Total hits: 5


Match Name	E-value	Identity	Description
gi\|13124785\|sp\|P16519\|NEC2_HUMAN	0.000e+0	59.97	RecName: Full=Neuroendocrine convertase 2; Short=N...	[more]
gi\|75061998\|sp\|Q5REC2\|NEC2_PONAB	0.000e+0	59.97	RecName: Full=Neuroendocrine convertase 2; Short=N...	[more]
gi\|128004\|sp\|P28841\|NEC2_RAT	0.000e+0	57.36	RecName: Full=Neuroendocrine convertase 2; Short=N...	[more]
gi\|128003\|sp\|P21661\|NEC2_MOUSE	0.000e+0	57.36	RecName: Full=Neuroendocrine convertase 2; Short=N...	[more]
gi\|417351\|sp\|Q03333\|NEC2_PIG	0.000e+0	59.64	RecName: Full=Neuroendocrine convertase 2; Short=N...	[more]

BLAST of pc2 vs. RefSeq Drosophila melanogaster
Analysis Date: 2016-03-09 (Girardia Sp. BLASTX Drosophila melanogaster)
Total hits: 5


Match Name	E-value	Identity	Description
gi\|17136192\|ref\|NP_477318.1\|	0.000e+0	60.70	amontillado [Drosophila melanogaster]	[more]
gi\|281360987\|ref\|NP_001162774.1\|	7.879e-131	42.99	furin 2, isoform I [Drosophila melanogaster]	[more]
gi\|24642484\|ref\|NP_727963.1\|	4.702e-128	41.78	furin 2, isoform A [Drosophila melanogaster]	[more]
gi\|24642486\|ref\|NP_727964.1\|	4.702e-128	41.78	furin 2, isoform B [Drosophila melanogaster]	[more]
gi\|24642488\|ref\|NP_727965.1\|	4.702e-128	41.78	furin 2, isoform C [Drosophila melanogaster]	[more]

BLAST of pc2 vs. Smed Unigenes AA
Analysis Date: 2016-03-09 (Girardia Sp. BLASTX Schmidtea mediterranea)
Total hits: 5


Match Name	E-value	Identity	Description
SMU15019018	0.000e+0	93.49	SmedSxldir_c108536_g2_i2\|m.79117\|m.1373	[more]
SMU15036165	9.640e-122	39.84	SmedSxlregen_c89995_g1_i1\|m.42695\|m.12874	[more]
SMU15033125	7.352e-106	37.16	SmedSxlregen_c82367_g1_i3\|m.22377\|m.8734	[more]
SMU15002657	1.099e-105	37.16	Asxlregen_comp67843_c0_seq3\|m.34885\|m.51170	[more]
SMU15000885	1.359e-96	39.26	Asxlregen_comp60502_c0_seq1\|m.9253\|m.45850	[more]

Sequences

The following sequences are available for this feature:

mRNA sequence
protein sequence
coding sequence

mRNA sequence

>Gsp_010792 ID=Gsp_010792|Name=pc2|organism=Girardia sp.|type=mRNA|length=2205bp
ACAAACAACAAAACATACAGTTTAGAAAGCTGAAAAAAATCTTTATTAAA
ATTATTTTTTTAATTAAAAATTTCATTTTTCGATGTATCGAATATCGCTT
CTTTTTTTAATACAAATTTATACAATATATGGGAAAATTGTAACAAATCA
GTGGCATGTACGTCTTCATGATCCCGGAACTCATGATCTAGCCAATAAAG
TAGCTCAAGAAACTGGTTTCTCACTATTGAGAAACCATATACAATCTCCA
AATGAATTTGTTTACCATCATAAAGCTGTGCCCCATGTGAGTTCAATTCC
AAGTTGGAATCATCATAAAGTTTTATTATCTCATCCACTTGTTAAAGAAG
CTAAACAAGTTGAAGGTTTTATTAGAAAAAAACGAGGTTTTAAACCGATC
AAAAAGCAAGATCGTATTCCACTTCCAACAATAAACAAAAAAGGTATTCC
TGGCAGAGGAAAAACAGAGAACATTAAAGAAAATATGAAATTACCAACTG
ATCCTTTGTTTTCAAAAGAATGGTACATTCGAAACACTGGACAAGCTGAT
GGAGTAAAAGATCTTGATCTAAATGTTTTATCCGCATGGGCTCAAGGCAT
TACTGGTAAAGGTGTTACAACAGCAATTATGGATGACGGTATCGATTATC
TTCATCCAGATTTATCGAAAAATTACAATGCAGAAAGTAGTTATGATTTC
AGTAGTAACGATCCATATCCATTTCCAAGGTATACTGATGATTGGTTTAA
TAGTCATGGAACAAGATGCGCCGGTGAAATTTCAGCTGAGAGAGACAATG
GAATTTGTGGTGTTGGTGTGGCCTACAATTCTAAGATCGCCGGATTGCGT
ATGTTGGATCAACCGTATATGACAGATCTTATTGAAGCAGCAGCAATGAG
TTATGATAGAGATAATATTGATATTTATTCTGCCAGTTGGGGTCCTACAG
ATGATGGTAGAACAGTCGATGGACCAAGAAATGAGACCATGCGTGCAATT
GTAGAAGGCGTTAATAAAGGTCGTAAAGGTAAAGGAAGCATTTACGTTTG
GGCATCTGGTGATGGAGGAGCAGCCGATGATTGCAATTGCGACGGATATG
CAGCAAGCATGTGGACTATTAGTATTAATTCTGCAACCAATGATGGAGAA
ACTGCAAGCTACGATGAATCTTGTTCTTCAACCCTTGCCTCAACATTTTC
AAATGGAAAAGCATGGTTTAGTCTTGACGCAGGAGTTGGTACGGTTGATT
TATATGGACAATGCACCTTACATCATTCTGGAACTTCTGCTGCGGCCCCG
GAAGCAGCTGGAGTATTTGCTTTAGCTTTAGAAGCTAATTCTAATATTGG
TTGGAGAGACATGCAACATTTAACTGTGCTCACTAGTAAACGAAACCATT
TGCACGATCGAGATCGACGTCATAATTGGACAATTAATGGGGCCGGTTTG
GAATTTAATCATCTTTTTGGTTATGGAGTTCTTGATGCTGGTGATATGGT
TCGTGTTGCTAAAAAATGGGTAAATGTTCCTGAAAGATTTCACTGTATAG
CGGGACAAATTAATAAACGTTATCGGTTTAATGTTACTAAAGCACTGATA
CTCGAGATAGATACCGATGCTTGCAAATCAGATACTGGCCATCGAGTTAA
TTATCTAGAACATGTTCAAGCTTTTATATCAGTAAAAGCTAGTAGACGAG
GAGATATAACAATGTTTCTTACCAGCCCAATGGGCACAACATCTATGATT
CTCAGTCATCGACCAAAAGACGATGATTCTACACGAGGATTTACAAAATG
GCCATTTATGACCACGCATACATGGGGTGAAAATCCTCGTGGAAAATGGC
GATTAACAATAATGTTCGACACAAAAGATCCTCTTAGTCAAGGAATATTT
TCGGAATGGGTTCTTGTTTTGCATGGAACTCAAAATCGACCATATGATAA
ACTATCTAGTTCTTTGGAAAAGATTATACCTAAGCTCGGTGTAGTAAAGA
GACAACATGCCTCCAACAGATTTTCCCAATAGTTGAACTGACATTCGTTT
AGCATTTTATGTTTACGATAGCAGTTTTACTGCAGATTTTTGTGATTGTA
TTTTTGTAAACTTTTGTCCAGTGAGATTGTGATATCTTATTATTACTATT
ATTATTAATTTTACTATCATCTCATCGACATGATTATTAAATATATTTGT
CTTGT

Design Primers for pc2

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protein sequence

>Gsp_010792-protein ID=Gsp_010792-protein|Name=pc2|organism=Girardia sp.|type=polypeptide|length=650bp

MYRISLLFLIQIYTIYGKIVTNQWHVRLHDPGTHDLANKVAQETGFSLLR
NHIQSPNEFVYHHKAVPHVSSIPSWNHHKVLLSHPLVKEAKQVEGFIRKK
RGFKPIKKQDRIPLPTINKKGIPGRGKTENIKENMKLPTDPLFSKEWYIR
NTGQADGVKDLDLNVLSAWAQGITGKGVTTAIMDDGIDYLHPDLSKNYNA
ESSYDFSSNDPYPFPRYTDDWFNSHGTRCAGEISAERDNGICGVGVAYNS
KIAGLRMLDQPYMTDLIEAAAMSYDRDNIDIYSASWGPTDDGRTVDGPRN
ETMRAIVEGVNKGRKGKGSIYVWASGDGGAADDCNCDGYAASMWTISINS
ATNDGETASYDESCSSTLASTFSNGKAWFSLDAGVGTVDLYGQCTLHHSG
TSAAAPEAAGVFALALEANSNIGWRDMQHLTVLTSKRNHLHDRDRRHNWT
INGAGLEFNHLFGYGVLDAGDMVRVAKKWVNVPERFHCIAGQINKRYRFN
VTKALILEIDTDACKSDTGHRVNYLEHVQAFISVKASRRGDITMFLTSPM
GTTSMILSHRPKDDDSTRGFTKWPFMTTHTWGENPRGKWRLTIMFDTKDP
LSQGIFSEWVLVLHGTQNRPYDKLSSSLEKIIPKLGVVKRQHASNRFSQ*

coding sequence

>Gsp_010792.83.2032 ID=Gsp_010792.83.2032|Name=Gsp_010792.83.2032|organism=Girardia sp.|type=CDS|length=1950bp
ATGTATCGAATATCGCTTCTTTTTTTAATACAAATTTATACAATATATGG
GAAAATTGTAACAAATCAGTGGCATGTACGTCTTCATGATCCCGGAACTC
ATGATCTAGCCAATAAAGTAGCTCAAGAAACTGGTTTCTCACTATTGAGA
AACCATATACAATCTCCAAATGAATTTGTTTACCATCATAAAGCTGTGCC
CCATGTGAGTTCAATTCCAAGTTGGAATCATCATAAAGTTTTATTATCTC
ATCCACTTGTTAAAGAAGCTAAACAAGTTGAAGGTTTTATTAGAAAAAAA
CGAGGTTTTAAACCGATCAAAAAGCAAGATCGTATTCCACTTCCAACAAT
AAACAAAAAAGGTATTCCTGGCAGAGGAAAAACAGAGAACATTAAAGAAA
ATATGAAATTACCAACTGATCCTTTGTTTTCAAAAGAATGGTACATTCGA
AACACTGGACAAGCTGATGGAGTAAAAGATCTTGATCTAAATGTTTTATC
CGCATGGGCTCAAGGCATTACTGGTAAAGGTGTTACAACAGCAATTATGG
ATGACGGTATCGATTATCTTCATCCAGATTTATCGAAAAATTACAATGCA
GAAAGTAGTTATGATTTCAGTAGTAACGATCCATATCCATTTCCAAGGTA
TACTGATGATTGGTTTAATAGTCATGGAACAAGATGCGCCGGTGAAATTT
CAGCTGAGAGAGACAATGGAATTTGTGGTGTTGGTGTGGCCTACAATTCT
AAGATCGCCGGATTGCGTATGTTGGATCAACCGTATATGACAGATCTTAT
TGAAGCAGCAGCAATGAGTTATGATAGAGATAATATTGATATTTATTCTG
CCAGTTGGGGTCCTACAGATGATGGTAGAACAGTCGATGGACCAAGAAAT
GAGACCATGCGTGCAATTGTAGAAGGCGTTAATAAAGGTCGTAAAGGTAA
AGGAAGCATTTACGTTTGGGCATCTGGTGATGGAGGAGCAGCCGATGATT
GCAATTGCGACGGATATGCAGCAAGCATGTGGACTATTAGTATTAATTCT
GCAACCAATGATGGAGAAACTGCAAGCTACGATGAATCTTGTTCTTCAAC
CCTTGCCTCAACATTTTCAAATGGAAAAGCATGGTTTAGTCTTGACGCAG
GAGTTGGTACGGTTGATTTATATGGACAATGCACCTTACATCATTCTGGA
ACTTCTGCTGCGGCCCCGGAAGCAGCTGGAGTATTTGCTTTAGCTTTAGA
AGCTAATTCTAATATTGGTTGGAGAGACATGCAACATTTAACTGTGCTCA
CTAGTAAACGAAACCATTTGCACGATCGAGATCGACGTCATAATTGGACA
ATTAATGGGGCCGGTTTGGAATTTAATCATCTTTTTGGTTATGGAGTTCT
TGATGCTGGTGATATGGTTCGTGTTGCTAAAAAATGGGTAAATGTTCCTG
AAAGATTTCACTGTATAGCGGGACAAATTAATAAACGTTATCGGTTTAAT
GTTACTAAAGCACTGATACTCGAGATAGATACCGATGCTTGCAAATCAGA
TACTGGCCATCGAGTTAATTATCTAGAACATGTTCAAGCTTTTATATCAG
TAAAAGCTAGTAGACGAGGAGATATAACAATGTTTCTTACCAGCCCAATG
GGCACAACATCTATGATTCTCAGTCATCGACCAAAAGACGATGATTCTAC
ACGAGGATTTACAAAATGGCCATTTATGACCACGCATACATGGGGTGAAA
ATCCTCGTGGAAAATGGCGATTAACAATAATGTTCGACACAAAAGATCCT
CTTAGTCAAGGAATATTTTCGGAATGGGTTCTTGTTTTGCATGGAACTCA
AAATCGACCATATGATAAACTATCTAGTTCTTTGGAAAAGATTATACCTA
AGCTCGGTGTAGTAAAGAGACAACATGCCTCCAACAGATTTTCCCAATAG

Gene Groups

pc2 is similar in sequence to the genes of this group: GG3186


Gene Name	Gene ID
SMU15019018	SMU15019018
pc2	Ddo_018155
pc2	Gsp_010792
pc2	Pgr_003685
Pgr_007588	Pgr_007588
pc2	Pmo_008419
Pmo_028616	Pmo_028616

Gene Group Protein Sequences

>SMU15019018

MKITWILLFLCEYVVCGKIVTNQWHVHLHDPATQESANKVAQETGFSVLR
NHLNSPNEFVFHHKTVPHVSSVPSWSQHKVLLAHHLVKNAKQVEGFLRRK
RGYKPIKKQGRVPLPTINKKGIPGLGESDNIKVDLKLPTDPLFSKEWYIR
NTGQADGVKDLDLNVLSAWAQGITGKGVTTAIMDDGIDYLHPDLSKNYNA
ESSYDFSSNDPYPFPRYTDDWFNSHGTRCAGEISAERDNGICGVGVAYDS
KIAGLRMLDQPYMTDLIEAAAMSYDRDNIDIYSASWGPTDDGRTVDGPRN
ETMRAIVEGVNKGRKGKGSIYVWASGDGGAADDCNCDGYAASMWTISINS
ATNDGETASYDESCSSTLASTFSNGKAWFSLDAGVGTVDLYGQCTLHHSG
TSAAAPEAAGVFALALEANSNIGWRDMQHLTVLTSKRNHLHDRDRRHNWT
INGAGLEFNHLFGYGVLDAGDMVRVAKKWVNVPERFHCIAGQIDKRYRFN
VTKALILEIDTDACKSDIGHRVNYLEHVQAFVSVKSSRRGDITMFLTSPM
GTTSMILSHRPKDDDSTRGFTKWPFMTTHTWGENPRGKWKLTVMFDTKDP
LSQGIFSEWVLVLHGTQSRPYDKLSSSLEKIIPKLGVVKRQHASNRFSQ*

>Ddo_018155 pc2

MMFLWILTTLQIYLINGKIVTNQWHVSLHHPGDEEVANKVAQETGFSVLR
GHLKTPGEFVFSHKALPQASAIPSWTHHKILLAHPQVKNAKQVEGFLRKK
RGYKPIKKQARIPLPTINKKGIPGREATDNIKNMNLPTDPLFSKEWYIRN
TGQAEGVKDLDLNVLSAWSQGITGKGVTTAIMDDGIDYLHPDLSKNYNAE
SSYDFSSNDPYPFPRYTDDWFNSHGTRCAGEISAERDNGICGVGVAYDSK
IAGLRMLDQPYMTDLIEAAAMSYDRDNIDIYSASWGPTDDGRTVDGPRNE
TMRAIVEGVNKGRKGKGSIYVWASGDGGAADDCNCDGYAASMWTISINSA
TNDGETASYDESCSSTLASTFSNGKAWFSLDAGVGTVDLYGQCTLHHSGT
SAAAPEAAGVFALALEANPEIGWRDMQHLTVLTSKRNHLHDRDRRHNWTI
NGAGLEFNHLFGYGVLDAGDMVRVAKRWVNVPERFHCIAGQIDKRYRFNV
SRALILEIDTDACKSDSGHRVNYLEHVQAFVSVKATRRGDITMFLTSPMG
TTSMILSHRPKDDDSSRGFTKWPFMTTHTWGENPRGKWRLTVMFETKEPL
SQGLFTEWVLVLHGTQNRPYDKLSSSLEKIIPKLGVVKRQHASKRFMQ*

>Gsp_010792 pc2

MYRISLLFLIQIYTIYGKIVTNQWHVRLHDPGTHDLANKVAQETGFSLLR
NHIQSPNEFVYHHKAVPHVSSIPSWNHHKVLLSHPLVKEAKQVEGFIRKK
RGFKPIKKQDRIPLPTINKKGIPGRGKTENIKENMKLPTDPLFSKEWYIR
NTGQADGVKDLDLNVLSAWAQGITGKGVTTAIMDDGIDYLHPDLSKNYNA
ESSYDFSSNDPYPFPRYTDDWFNSHGTRCAGEISAERDNGICGVGVAYNS
KIAGLRMLDQPYMTDLIEAAAMSYDRDNIDIYSASWGPTDDGRTVDGPRN
ETMRAIVEGVNKGRKGKGSIYVWASGDGGAADDCNCDGYAASMWTISINS
ATNDGETASYDESCSSTLASTFSNGKAWFSLDAGVGTVDLYGQCTLHHSG
TSAAAPEAAGVFALALEANSNIGWRDMQHLTVLTSKRNHLHDRDRRHNWT
INGAGLEFNHLFGYGVLDAGDMVRVAKKWVNVPERFHCIAGQINKRYRFN
VTKALILEIDTDACKSDTGHRVNYLEHVQAFISVKASRRGDITMFLTSPM
GTTSMILSHRPKDDDSTRGFTKWPFMTTHTWGENPRGKWRLTIMFDTKDP
LSQGIFSEWVLVLHGTQNRPYDKLSSSLEKIIPKLGVVKRQHASNRFSQ*

>Pgr_003685 pc2

MKFYLTIWICLIAASKRSWAGIHTNQWHVHLHEPGENMAKKVAAETGFSL
LRSHFKSPNEFIFTHKAIPEVSAVPSWSHHMNLVAHPMVKQANQAEGYLR
KKRGYKPVKRDRIPLPSINKKGIPDREKVKNENIKLPTDPLFAKEWYIRN
TGQAEGVKDLDLNVLSAWAQGITGKGVTTAIMDDGIDYLHPDLSKNYNAE
SSYDFSSNDPYPFPRYTDDWFNSHGTRCAGEISAERDNGVCGVGIAYDSK
VVGLRMLDQPYMTDLIESAAMSHDRDSIHIYSASWGPTDDGRTVDGPRNE
TMKAIVDGVNKGRHGKGNIYVWASGDGGVADDCNCDGYAASMWTISINSA
TNDGETASYDESCSSTLASTFSNGKAWYSLDAGVGTVDLYGQCTLHHSGT
SAAAPEAAAVFALALEANTNIGWRDMQHLSVLTSKRNHLHDRDQRHNWTI
NGAGLEFNHLFGYGVLDAGDMVRVAKQWVNVPERFHCIAGTIDKRMIFNV
SKALVLEIDTDACKLDEAHMVNYLEHVQAFVTVKASRRGDITMFLTSPMG
TTSMILSRREKDDDPSRGFTKWPFMTTHTWGENPRGKWRLTVMFDTEDAL
SQGLFSEWILVLHGTQTPPYDKLSASLETIIPKLAAVKRQHASKTFLQ*

>Pgr_007588 Pgr_007588

MHFYLIFWLFVLSGVRESLAKIHSNQWYVRLHESGDDAAKRVASETGFVY
LRNHLQSPHEFIFTHRGIADASAAPSVSHQMNLLAHPMVKQASQMEGFLR
RKRGYKPVKKLPLQLTNINKKGIPDREKNSTDAHSQRRLPRDPLFSKEWY
ILNTGQAEGVKDLDLNVLSAWDQGVTGKGITTAIMDDGIDYLHPDLSKNY
NAENSYDFSSNDPYPFPRYTDDWFNSHGTRCAGEISAERDNDICGVGIAY
NSKVAGLRMLDQPYMTDLIEASAMSHDRDMIDIYSASWGPTDDGRTVDGP
RNETMRAIVDGVNKGRNGRGSIYVWASGDGGMSDDCNCDGYAASMWTISI
NSATNDGETASYDESCSSTLASTFSNGKAWFSLDAGVGTVDLYGQCTLLH
SGTSAAAPEAAAVFALALEANREIGWRDMQHLSVLTSKRNHLHDRDGRHN
WTINGAGLEFNHLFGYGVLDAGDMVRVAKKWINVPERFHCIAGEISERSR
FNISKALILEINTDACKSSDGHRVNYLEHVQAFVTVRASRRGDVTLFLTS
PMGTTSMILSRRVKDGDSMQGFTKWPFMTTHTWGENPRGKWRLMAMFDTD
DALSQGVLSEWILVLHGTQERPYDKLSSSLEKILPKLAVIKRQHASKNFL
Q*

>Pmo_008419 pc2

MRVAILVSVIVVLLSHRLTATIHSNQWHVHLQQPGEHVAEQVASETGFSL
LRNHLRSPNEFIFTHRALPPASAVASLSHHMNLVAHPLVKQATQMEGFLR
KKRGYKPIKRQRVPLPSIDKKGIPDRLKERSNKESIKLPTDPLFEKEWYI
RNTGQAEGVKDLDLNVLSAWSQGITGKGITTAIMDDGIDYLHSDLSRNYN
AESSYDFSSNDPYPFPRYTDDWFNSHGTRCAGEISAERDNGVCGVGIAYN
SQVAGLRMLDQPYMTDLIEAAAMSHDRDNIHIYSASWGPTDDGRTVDGPR
NETMRAIVDGVNKGRNGKGNIYVWASGDGGASDDCNCDGYAASMWTISIN
SATNDGETASYDESCSSTLASTFSNGKAWFSLDAGVGTVDLYGQCTLHHS
GTSAAAPEAAAVFALALEANGEMGWRDMQHLSVLTSKRNHLHDRDGRHNW
TINGAGLEFNHLFGYGVLDAGDMVRVAKMWANVPERFHCIAGEINQKSRF
NISKALVLEIDTDACKSDDNHRVNYLEHVQAFVTVKASRRGDITMFLTSP
MGTTSMILSRREKDSDSIRGFTKWPFMTTHTWGETPRGKWRLTVMFDTED
ALIQGLLSEWV

>Pmo_028616 Pmo_028616

MDDGIDYLHPDLSKNYNAESSYDFSSNDPYPFPRYTDDWFNSHGTRCAGE
ISAERDNGVCGVGIAYNSQVVGLRMLDQPYMTDLIESAAMSHERDSIDIY
SASWGPTDDGRTVDGPRNETMKAIVDGVNKGRRGKGNIYVWASGDGGVAD
DCNCDGYAASMWTISINSATNDGETASYDESCSSTLASTFSNGKAWYSLD
AGVGTVDLYGQCTLHHSGTSAAAPEAAAVFALALEANTNIGWRDMQHLSV
LTSKRNHLHDRDQRHNWTINGAGLEFNHLFGYGVLDAGDMVRVAKQWVNV
PERFHCIAGQIDHKARFNVTKALILEIDTDACKSDDGHRVNYLEHVQAFV
TVKASRRGDTTMFLTSPMGTTSMILSRREKDSDSIRGFTKWPFMTTHTWG
ENPRGKWRLTVMFDTEDALSQGMFSEWILLLHGTQIPPYDKLSTSLEKII
PKLAAVKRQHASKKFLE*

pc2, Gsp_010792 (mRNA) Girardia sp.

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pc2, Gsp_010792 (mRNA) Girardia sp.

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