sfrp-1, Ddo_009225 (mRNA) Dugesia dorotocephala

Overview
Namesfrp-1
Unique NameDdo_009225
TypemRNA
OrganismDugesia dorotocephala (D. dorotocephala)
Sequence length1153
Analyses
This mRNA is derived from or has results from the following analyses
Analysis NameDate Performed
Dugesia dorotocephala Transcriptome2016-03-03
Dugesia dorotocephala BLASTX Human2016-03-08
Dugesia dorotocephala BLASTX Drosophila melanogaster2016-03-08
Dugesia dorotocephala BLASTX Swissprot Uniprot2016-03-07
Dugesia dorotocephala BLASTX Schmidtea mediterranea2016-03-08
Dugesia dorotocephala CDS2016-04-26
Properties
Property NameValue
NoteSfrp-1
Homology
BLAST of sfrp-1 vs. uniprot
Match: gi|61216765|sp|P97299|SFRP2_MOUSE (RecName: Full=Secreted frizzled-related protein 2; Short=sFRP-2; AltName: Full=Protein SDF5; AltName: Full=Secreted apoptosis-related protein 1; Short=SARP-1; Flags: Precursor)

HSP 1 Score: 140.198 bits (352), Expect = 9.36132e-37
Identity = 74/200 (37.00%), Postives = 103/200 (51.50%), Query Frame = 3
Query:  126 GYTTDQCYKVPENFSMCHNVGYNKMVLPNFIQHEYMEEAIAHSRVWLSLVKSQCHLDVRKFLCSLYAPVCITNKRIQKVPPCRELCIIVKEACLPSMKMYGFNWPEIMKCSKFPPVQNALCI---------PKTTVKKKNCELC-VKNAPYEVIANRFCLSPIVIRAKIKRIIPKESGFQIVLHQKSKFL-KFQSNSSRD 692
Y C +P N +CH + Y M LPN + HE M+E + + W+ LV QCH D +KFLCSL+APVC+ + + + PC LC+ VK+ C P M +GF WP++++C +F P N LCI P T K CE C KN I C + ++ K+K I +I+L KSK + K S RD
Sbjct: 34 SYKRSNCKPIPANLQLCHGIEYQNMRLPNLLGHETMKEVLEQAGAWIPLVMKQCHPDTKKFLCSLFAPVCLDDLD-ETIQPCHSLCVQVKDRCAPVMSAFGFPWPDMLECDRF-PQDNDLCIPLASSDHLLPATEEAPKVCEACKTKNEDDNDIMETLCKNDFALKIKVKEITYINRDTKIILETKSKTIYKLNGVSERD 231
BLAST of sfrp-1 vs. uniprot
Match: gi|61216791|sp|Q863H1|SFRP2_CANFA (RecName: Full=Secreted frizzled-related protein 2; Short=sFRP-2; Flags: Precursor [Canis lupus familiaris])

HSP 1 Score: 139.428 bits (350), Expect = 1.89803e-36
Identity = 74/200 (37.00%), Postives = 103/200 (51.50%), Query Frame = 3
Query:  126 GYTTDQCYKVPENFSMCHNVGYNKMVLPNFIQHEYMEEAIAHSRVWLSLVKSQCHLDVRKFLCSLYAPVCITNKRIQKVPPCRELCIIVKEACLPSMKMYGFNWPEIMKCSKFPPVQNALCI---------PKTTVKKKNCELCV-KNAPYEVIANRFCLSPIVIRAKIKRIIPKESGFQIVLHQKSKFL-KFQSNSSRD 692
Y C +P N +CH + Y M LPN + HE M+E + + W+ LV QCH D +KFLCSL+APVC+ + + + PC LC+ VK+ C P M +GF WP++++C +F P N LCI P T K CE C KN I C + ++ K+K I +I+L KSK + K S RD
Sbjct: 33 SYKRSNCKPIPANLQLCHGIEYQNMRLPNLLGHETMKEVLEQAGAWIPLVMKQCHPDTKKFLCSLFAPVCLDDLD-ETIQPCHSLCVQVKDRCAPVMSAFGFPWPDMLECDRF-PQDNDLCIPLASSDHLLPATEEAPKVCEACKNKNEDDNDIMETLCKNDFALKIKVKEITYINRDTKIILETKSKTIYKLNGVSERD 230
BLAST of sfrp-1 vs. uniprot
Match: gi|61216828|sp|Q96HF1|SFRP2_HUMAN (RecName: Full=Secreted frizzled-related protein 2; Short=FRP-2; Short=sFRP-2; AltName: Full=Secreted apoptosis-related protein 1; Short=SARP-1; Flags: Precursor)

HSP 1 Score: 139.428 bits (350), Expect = 1.9187e-36
Identity = 74/200 (37.00%), Postives = 103/200 (51.50%), Query Frame = 3
Query:  126 GYTTDQCYKVPENFSMCHNVGYNKMVLPNFIQHEYMEEAIAHSRVWLSLVKSQCHLDVRKFLCSLYAPVCITNKRIQKVPPCRELCIIVKEACLPSMKMYGFNWPEIMKCSKFPPVQNALCI---------PKTTVKKKNCELCV-KNAPYEVIANRFCLSPIVIRAKIKRIIPKESGFQIVLHQKSKFL-KFQSNSSRD 692
Y C +P N +CH + Y M LPN + HE M+E + + W+ LV QCH D +KFLCSL+APVC+ + + + PC LC+ VK+ C P M +GF WP++++C +F P N LCI P T K CE C KN I C + ++ K+K I +I+L KSK + K S RD
Sbjct: 34 SYKRSNCKPIPANLQLCHGIEYQNMRLPNLLGHETMKEVLEQAGAWIPLVMKQCHPDTKKFLCSLFAPVCLDDLD-ETIQPCHSLCVQVKDRCAPVMSAFGFPWPDMLECDRF-PQDNDLCIPLASSDHLLPATEEAPKVCEACKNKNDDDNDIMETLCKNDFALKIKVKEITYINRDTKIILETKSKTIYKLNGVSERD 231
BLAST of sfrp-1 vs. uniprot
Match: gi|341942099|sp|Q8C4U3|SFRP1_MOUSE (RecName: Full=Secreted frizzled-related protein 1; Short=sFRP-1; Flags: Precursor)

HSP 1 Score: 138.658 bits (348), Expect = 5.87387e-36
Identity = 74/186 (39.78%), Postives = 102/186 (54.84%), Query Frame = 3
Query:   99 IGDWESFRSGYTTDQCYKVPENFSMCHNVGYNKMVLPNFIQHEYMEEAIAHSRVWLSLVKSQCHLDVRKFLCSLYAPVCITNKRIQKVPPCRELCIIVKEACLPSMKMYGFNWPEIMKCSKFPPVQNALCI----PKTTVKKKN-----CELCVKNAPYEVIANRFCLSPIVIRAKIKRIIPKESG 629
IG ++S R QC +P + +CHNVGY KMVLPN ++HE M E + W+ L+ CH+ + FLCSL+APVC+ + + PCR LC V+++C P M+ +GF WPE++KC KFP + +CI P TT K C C E I C S +R KIK + KE+G
Sbjct: 43 IGSYQSGRFYTKPPQCVDIPVDLRLCHNVGYKKMVLPNLLEHETMAEVKQQASSWVPLLNKNCHMGTQVFLCSLFAPVCLD----RPIYPCRWLCEAVRDSCEPVMQFFGFYWPEMLKCDKFP--EGDVCIAMTPPNTTEASKPQGTTVCPPCDNELKSEAIIEHLCASEFALRMKIKE-VKKENG 221
BLAST of sfrp-1 vs. uniprot
Match: gi|61216839|sp|Q9DEQ4|SFRP1_CHICK (RecName: Full=Secreted frizzled-related protein 1; Short=CsFRP1; Short=sFRP-1; Flags: Precursor)

HSP 1 Score: 138.272 bits (347), Expect = 9.32062e-36
Identity = 72/200 (36.00%), Postives = 107/200 (53.50%), Query Frame = 3
Query:   99 IGDWESFRSGYTTDQCYKVPENFSMCHNVGYNKMVLPNFIQHEYMEEAIAHSRVWLSLVKSQCHLDVRKFLCSLYAPVCITNKRIQKVPPCRELCIIVKEACLPSMKMYGFNWPEIMKCSKFPPVQNALCIPKTTVKKKN---------CELCVKNAPYEVIANRFCLSPIVIRAKIKRIIPKESGFQIVLHQKSKFLKF 671
+G + R QC +P + +CH+VGY+KMVLPN + HE M E + W+ L+ CH+ + FLCSL+APVC+ + V PCR LC V+++C P M+ +GF WPE++KC +FP Q+ +CI TT C C E I C S ++ IK + KE+G ++++ +K K LK
Sbjct: 43 LGPYPGGRFYTKPHQCVAIPADLRLCHSVGYDKMVLPNLLDHETMAEVKHQASSWVPLLNKNCHMGTQVFLCSLFAPVCLD----RPVYPCRWLCEAVRDSCEPVMQFFGFFWPEMLKCDQFP--QDYVCIAMTTPNATEVSRPKGTTVCPPCDNEMKSEAIVEHLCASEFALKMTIKEVK-KENGDKVIIPRKRKALKL 235
BLAST of sfrp-1 vs. Smed Unigenes AA
Match: SMU15001274 (Asxlregen_comp63361_c0_seq1|m.13574|m.6037)

HSP 1 Score: 394.43 bits (1012), Expect = 3.32753e-135
Identity = 209/299 (69.90%), Postives = 256/299 (85.62%), Query Frame = 3
Query:   81 SNGNCFIGDWESFRSGYTTDQCYKVPENFSMCHNVGYNKMVLPNFIQHEYMEEAIAHSRVWLSLVKSQCHLDVRKFLCSLYAPVCITNKRIQKVPPCRELCIIVKEACLPSMKMYGFNWPEIMKCSKFPPVQNALCIPKTTVKKKNCELCVKNAPYEVIANRFCLSPIVIRAKIKRIIPKE-SGFQIVLHQKSKFLKFQSNSSRDSVXXXXXXXXXXXXFQQRALRGRWIIMARIVED-RFVVXXXXXXXXXXXXXXXXXRIIQKFGNVVCKSKLKDGISLQERYVAYMKMNNKTNYQN 971
SN N FIGDW++F+SGYT DQCY++P+NF++C NVGY MVLPN+IQHE +EEA HS+VW+ LV +QCH+D++KF+CSLYAPVCI+N+R QKVPPCRELC+ VKE+CLPSMKMYGF+WP IMKCSKFP +N+LCIPKT V K C+LC+K A YEVIANRFCLSPIVIRAKIKRIIP + QI+L +KSKFLKFQ+N S++++ L LKCNC NLKF+QRAL+GRWIIMA+I D + VVNFISKWK+KK EFK+S++IIQ FG++VCKSKL DGISL+ERY AY+KMNN+ Y N
Sbjct: 16 SNVNSFIGDWQAFQSGYTIDQCYQIPDNFTLCSNVGYRLMVLPNYIQHESIEEAAQHSKVWMGLVNTQCHVDIKKFICSLYAPVCISNQRNQKVPPCRELCVTVKESCLPSMKMYGFDWPTIMKCSKFPQFKNSLCIPKTVVPGKKCDLCMKIASYEVIANRFCLSPIVIRAKIKRIIPTSGNAIQIILQKKSKFLKFQANFSQNALELNLKCNCTNLKFKQRALKGRWIIMAQIDSDNKAVVNFISKWKRKKAEFKHSMKIIQNFGHIVCKSKLPDGISLRERYAAYLKMNNQLKYSN 314
BLAST of sfrp-1 vs. Smed Unigenes AA
Match: SMU15040524 (dd_smedV4_8832_0_1|m.39951|m.18186)

HSP 1 Score: 189.119 bits (479), Expect = 1.03558e-55
Identity = 114/302 (37.75%), Postives = 176/302 (58.28%), Query Frame = 3
Query:   99 IGDWESFRSGYTTDQCYKVPENFSMCHNVGYNKMVLPNFIQHEYMEEAIAHSRVWLSLVKSQCHLDVRKFLCSLYAPVCITNKRIQKVPPCRELCIIVKEACLPSMKMYGFNWPEIMKCSKFPPVQNALCIPKT---------TVKKKNCELCVKNAPYEVIANRFCLSPIVIRAKIKRI-IPKESGFQIVLHQKSKFLKFQSNSSRDSVXXXXXXXXXXXXFQQRALR-GRWIIMARIVEDRFVVXXXXXXXXXXXXXXXXXRIIQKFGNVVCKSKLKDGISLQERYVAYMKMNNKTNYQN 971
+ +W + GY++ +C+++P F +C N+GYNKM+LPNF+QHE ++EAI S W +CH D R+FLCSLYAPVC+ N+ ++K+ PC+ELC+ VK+AC P+M +G+ WPEI+ C KFP LCI T +V K C C I + +C S VIRAKI R+ I S + + LH+KSK +K SN + ++ +CL +R GRW++M + + +F + ++KWKKK ++FK IR ++KF +C S+ + +R ++ + +N QN
Sbjct: 25 VPEWNNLIYGYSSHRCHEIPNEFGLCKNIGYNKMILPNFLQHETVQEAINSSIDWQKFADIKCHNDTRRFLCSLYAPVCVPNEPVRKIQPCKELCLSVKKACSPNMLTFGYKWPEILHCDKFPQKFAGLCIRGTEGAVPSGSSSVVPKGCN-CRSLYSAAFINDNYCSSTTVIRAKISRLRIRNNSKYVMRLHKKSKIIK--SNPTDLPFITSIEVSCLCDMIDNDNIRKGRWLLMGVVNDGKFTLTSLTKWKKKNKDFKKVIRKLKKFEEKICGSRFR----ASDRKMSGLNINGGKMSQN 319
BLAST of sfrp-1 vs. Smed Unigenes AA
Match: SMU15030883 (SmedSxlregen_c55322_g1_i1|m.6956|m.30359)

HSP 1 Score: 139.043 bits (349), Expect = 8.7987e-37
Identity = 87/270 (32.22%), Postives = 126/270 (46.67%), Query Frame = 3
Query:  114 SFRSGYT---TDQCYKVPENFSMCHNVG-YNKM-VLPNFIQHEYMEEAIAHSRVWLSLVKSQCHLDVRKFLCSLYAPVCITNKRIQKVPPCRELCIIVKEACLPSMKMYGFNWPEIMKCSKFPPVQNALCIPKT-------------------------------TVKKKNCELCVKNAPYEVIANRFCLSPIVIRAKIKRIIPKESG-FQIVLHQKSKFLKFQSNSSRDSVXXXXXXXXXXXXFQQRA---LRGRWIIMARIVEDRFVV 803
FR G +QCY N ++C G N M +++ +I S +W+ L+ ++CH+D+ KFLC++YAP+C+ R +V PC ELC VKE CLP +K+YGF WP I+ C KFP A CI T T++KKNC +C + P E++ FC +VIRAKI I K G I L KS + S+ R S+ + Q A +G+W++ I +F+V
Sbjct: 20 DFRVGANRQRLNQCYPKFANHTLCGGAGVLNSMKTFSGLLRNSKSGFSIYQSNIWIILLHTKCHVDLEKFLCTIYAPICLKGHRFTRVFPCEELCASVKEQCLPRLKIYGFEWPSIVDCGKFPLENKASCIQLTDGTGNYLKKSLVKKQREDRSLNQTILSDQEQTLQKKNCPICNRKVPLEILTKNFCKYSLVIRAKIANIFQKPKGAISIRLQHKSNII-HSSHPIRISLANLITEIQCKCSILQNAKSVSKGKWLLFGDIENGQFIV 288
BLAST of sfrp-1 vs. Smed Unigenes AA
Match: SMU15001054 (Asxlregen_comp62015_c0_seq1|m.11130|m.22104)

HSP 1 Score: 102.834 bits (255), Expect = 9.95834e-24
Identity = 56/153 (36.60%), Postives = 83/153 (54.25%), Query Frame = 3
Query:  153 VPENFSMCHNVGYNKMVLPNFIQHEYMEEAIAHSRVWLSLVKSQCHLDVRKFLCSLYAPVCITNKRIQKVPPCRELCIIVKEACLPSMKMYGFNWPEIMKCSKFPPVQNALCIPKTTVKKKN-CELCVKNAPYEVIANR---FCLSPIVIRAK 599
+P SMC +GYN +PN + H +EEA + + +LV+ C D+R FLCS+YAP+C+ N ++P CR LCI +E C M YGF WPE M C K P ++ C+ K + N V PY + + + C SP++I ++
Sbjct: 36 IPIEISMCKGIGYNLTYIPNDLNHASLEEAGLEIQQFNALVEINCSEDLRLFLCSMYAPICLPNWP-NRIPACRSLCISAREGCTRVMNQYGFKWPEGMNCEKLP--EDNACLRKDNKTRSNKTANFVSERPYLLKSKKCHCHCRSPLIIDSR 185
BLAST of sfrp-1 vs. Smed Unigenes AA
Match: SMU15036199 (SmedSxlregen_c90692_g1_i1|m.42870|m.18187)

HSP 1 Score: 94.3597 bits (233), Expect = 7.9419e-21
Identity = 56/139 (40.29%), Postives = 71/139 (51.08%), Query Frame = 3
Query:  153 VPENFSMCHNVGYNKMVLPNFIQHEYMEEAIAHSRVWLSLVKSQCHLDVRKFLCSLYAPVCITN--KRIQKVPPCRELCIIVKEACLPSMKMYGFNWPEIMKCSKFPPVQNALCIPKTTVK-----KKNCELCVKNAPY 548
VP MC N+GYN +PN HE EEA + LV+ C ++R FLCSLYAP+C+ N K IQ CR +C ++ C P M YGF WP+ M C K +N C+ K T K CE C +PY
Sbjct: 60 VPIAIPMCKNIGYNLTYMPNEFHHETQEEAGLVVHQFYPLVEIACSDNLRLFLCSLYAPICLPNWPKPIQA---CRSVCESARDGCAPVMNTYGFKWPKSMDCDKL--TENQACLKKDTKNVTKPPSKGCE-CKCRSPY 192
BLAST of sfrp-1 vs. RefSeq Human
Match: gi|48475052|ref|NP_003004.1| (secreted frizzled-related protein 2 precursor [Homo sapiens])

HSP 1 Score: 139.428 bits (350), Expect = 7.24133e-37
Identity = 74/200 (37.00%), Postives = 103/200 (51.50%), Query Frame = 3
Query:  126 GYTTDQCYKVPENFSMCHNVGYNKMVLPNFIQHEYMEEAIAHSRVWLSLVKSQCHLDVRKFLCSLYAPVCITNKRIQKVPPCRELCIIVKEACLPSMKMYGFNWPEIMKCSKFPPVQNALCI---------PKTTVKKKNCELCV-KNAPYEVIANRFCLSPIVIRAKIKRIIPKESGFQIVLHQKSKFL-KFQSNSSRD 692
Y C +P N +CH + Y M LPN + HE M+E + + W+ LV QCH D +KFLCSL+APVC+ + + + PC LC+ VK+ C P M +GF WP++++C +F P N LCI P T K CE C KN I C + ++ K+K I +I+L KSK + K S RD
Sbjct: 34 SYKRSNCKPIPANLQLCHGIEYQNMRLPNLLGHETMKEVLEQAGAWIPLVMKQCHPDTKKFLCSLFAPVCLDDLD-ETIQPCHSLCVQVKDRCAPVMSAFGFPWPDMLECDRF-PQDNDLCIPLASSDHLLPATEEAPKVCEACKNKNDDDNDIMETLCKNDFALKIKVKEITYINRDTKIILETKSKTIYKLNGVSERD 231
BLAST of sfrp-1 vs. RefSeq Human
Match: gi|56117838|ref|NP_003003.3| (secreted frizzled-related protein 1 precursor [Homo sapiens])

HSP 1 Score: 135.576 bits (340), Expect = 2.82071e-35
Identity = 73/186 (39.25%), Postives = 100/186 (53.76%), Query Frame = 3
Query:   99 IGDWESFRSGYTTDQCYKVPENFSMCHNVGYNKMVLPNFIQHEYMEEAIAHSRVWLSLVKSQCHLDVRKFLCSLYAPVCITNKRIQKVPPCRELCIIVKEACLPSMKMYGFNWPEIMKCSKFPPVQNALCI----PKTTVKKKN-----CELCVKNAPYEVIANRFCLSPIVIRAKIKRIIPKESG 629
IG ++S R QC +P + +CHNVGY KMVLPN ++HE M E + W+ L+ CH + FLCSL+APVC+ + + PCR LC V+++C P M+ +GF WPE++KC KFP + +CI P T K C C E I C S +R KIK + KE+G
Sbjct: 43 IGPYQSGRFYTKPPQCVDIPADLRLCHNVGYKKMVLPNLLEHETMAEVKQQASSWVPLLNKNCHAGTQVFLCSLFAPVCLD----RPIYPCRWLCEAVRDSCEPVMQFFGFYWPEMLKCDKFP--EGDVCIAMTPPNATEASKPQGTTVCPPCDNELKSEAIIEHLCASEFALRMKIKEVK-KENG 221
BLAST of sfrp-1 vs. RefSeq Human
Match: gi|188528609|ref|NP_003006.2| (secreted frizzled-related protein 5 precursor [Homo sapiens])

HSP 1 Score: 129.413 bits (324), Expect = 5.26182e-33
Identity = 77/239 (32.22%), Postives = 116/239 (48.54%), Query Frame = 3
Query:  120 RSGYTTDQCYKVPENFSMCHNVGYNKMVLPNFIQHEYMEEAIAHSRVWLSLVKSQCHLDVRKFLCSLYAPVCITNKRIQKVPPCRELCIIVKEACLPSMKMYGFNWPEIMKCSKFPPVQNALCI-------PKTTVK-KKNCELCVKNAPYEVIANRFCLSPIVIRAKIKRIIPKESGFQIVLHQKSKFLKFQSNSSRDSVXXXXXXXXXXXXF---QQRALRGRWIIMARIVEDRFVV 803
RS QC +P + +CH VGY +M LPN ++HE + E + WL L+ +CH D + FLCSL+APVC+ + + PCR LC V+ C P M+ YGF WPE++ C KF P+ N LCI P T K C C + + + C S V++ +IK I + +++ QK K L R + Q +L G +++M R V+ + ++
Sbjct: 45 RSYSKPPQCLDIPADLPLCHTVGYKRMRLPNLLEHESLAEVKQQASSWLPLLAKRCHSDTQVFLCSLFAPVCLD----RPIYPCRSLCEAVRAGCAPLMEAYGFPWPEMLHCHKF-PLDNDLCIAVQFGHLPATAPPVTKICAQCEMEHSADGLMEQMCSSDFVVKMRIKEIKIENGDRKLIGAQKKKKLLKPGPLKRKDTKRLVLHMKNGAGCPCPQLDSLAGSFLVMGRKVDGQLLL 278
BLAST of sfrp-1 vs. RefSeq Human
Match: gi|4503825|ref|NP_003496.1| (frizzled-1 [Homo sapiens])

HSP 1 Score: 100.908 bits (250), Expect = 2.63371e-22
Identity = 49/129 (37.98%), Postives = 72/129 (55.81%), Query Frame = 3
Query:  138 DQCYKVPENFSMCHNVGYNKMVLPNFIQHEYMEEAIAHSRVWLSLVKSQCHLDVRKFLCSLYAPVCITNKRIQKVPPCRELCIIVKEACLPSMKMYGFNWPEIMKCSKFPPVQNA--LCIPKTTVKKKN 518
D Y P + +C ++ YN+ ++PN + H E+A + LVK QC +++ FLCS+YAPVC + Q +PPCR LC ++ C M +GF WP+ +KC KF PV A LC+ + T K
Sbjct: 112 DHGYCQPISIPLCTDIAYNQTIMPNLLGHTNQEDAGLEVHQFYPLVKVQCSAELKFFLCSMYAPVCTVLE--QALPPCRSLCERARQGCEALMNKFGFQWPDTLKCEKF-PVHGAGELCVGQNTSDKGT 237
BLAST of sfrp-1 vs. RefSeq Human
Match: gi|4503833|ref|NP_003498.1| (frizzled-7 precursor [Homo sapiens])

HSP 1 Score: 95.1301 bits (235), Expect = 2.13667e-20
Identity = 47/124 (37.90%), Postives = 69/124 (55.65%), Query Frame = 3
Query:  138 DQCYKVPENFSMCHNVGYNKMVLPNFIQHEYMEEAIAHSRVWLSLVKSQCHLDVRKFLCSLYAPVCITNKRIQKVPPCRELCIIVKEACLPSMKMYGFNWPEIMKCSKFPPVQNA--LCIPKTT 503
D + P + +C ++ YN+ +LPN + H E+A + LVK QC ++R FLCS+YAPVC Q +PPCR LC ++ C M +GF WPE ++C F PV A +C+ + T
Sbjct: 45 DHGFCQPISIPLCTDIAYNQTILPNLLGHTNQEDAGLEVHQFYPLVKVQCSPELRFFLCSMYAPVCTVLD--QAIPPCRSLCERARQGCEALMNKFGFQWPERLRCENF-PVHGAGEICVGQNT 165
BLAST of sfrp-1 vs. RefSeq Drosophila melanogaster
Match: gi|442632294|ref|NP_001261836.1| (frizzled, isoform C [Drosophila melanogaster])

HSP 1 Score: 92.8189 bits (229), Expect = 3.93356e-20
Identity = 48/104 (46.15%), Postives = 60/104 (57.69%), Query Frame = 3
Query:  156 PENFSMCHNVGYNKMVLPNFIQHEYMEEAIAHSRVWLSLVKSQCHLDVRKFLCSLYAPVCITNKRIQKVPPCRELCIIVKEACLPSMKMYGFNWPEIMKCSKFP 467
P S+C N+ YN ++PN I H EEA + LVK C D++ FLCSLY PVC +R +PPCR LC + C MK Y FNWPE ++CSKFP
Sbjct: 55 PITISICKNIPYNMTIMPNLIGHTKQEEAGLEVHQFAPLVKIGCSDDLQLFLCSLYVPVCTILER--PIPPCRSLCESAR-VCEKLMKTYNFNWPENLECSKFP 155
BLAST of sfrp-1 vs. RefSeq Drosophila melanogaster
Match: gi|17864440|ref|NP_524812.1| (frizzled, isoform A [Drosophila melanogaster])

HSP 1 Score: 92.4337 bits (228), Expect = 4.17834e-20
Identity = 48/104 (46.15%), Postives = 60/104 (57.69%), Query Frame = 3
Query:  156 PENFSMCHNVGYNKMVLPNFIQHEYMEEAIAHSRVWLSLVKSQCHLDVRKFLCSLYAPVCITNKRIQKVPPCRELCIIVKEACLPSMKMYGFNWPEIMKCSKFP 467
P S+C N+ YN ++PN I H EEA + LVK C D++ FLCSLY PVC +R +PPCR LC + C MK Y FNWPE ++CSKFP
Sbjct: 55 PITISICKNIPYNMTIMPNLIGHTKQEEAGLEVHQFAPLVKIGCSDDLQLFLCSLYVPVCTILER--PIPPCRSLCESAR-VCEKLMKTYNFNWPENLECSKFP 155
BLAST of sfrp-1 vs. RefSeq Drosophila melanogaster
Match: gi|442633302|ref|NP_001262037.1| (frizzled 2, isoform F [Drosophila melanogaster])

HSP 1 Score: 83.9593 bits (206), Expect = 3.55125e-17
Identity = 37/99 (37.37%), Postives = 54/99 (54.55%), Query Frame = 3
Query:  171 MCHNVGYNKMVLPNFIQHEYMEEAIAHSRVWLSLVKSQCHLDVRKFLCSLYAPVCITNKRIQKVPPCRELCIIVKEACLPSMKMYGFNWPEIMKCSKFP 467
MC +GYN PN + HE +EA + LV+ +C D++ FLCS+Y P+C+ + + +P CR +C + C P M+ Y F WPE M C P
Sbjct: 71 MCRGIGYNMTSFPNEMNHETQDEAGLEVHQFWPLVEIKCSPDLKFFLCSMYTPICLEDYH-KPLPVCRSVCERARSGCAPIMQQYSFEWPERMACEHLP 168
BLAST of sfrp-1 vs. RefSeq Drosophila melanogaster
Match: gi|17737633|ref|NP_524155.1| (frizzled 2, isoform A [Drosophila melanogaster])

HSP 1 Score: 83.9593 bits (206), Expect = 3.63181e-17
Identity = 37/99 (37.37%), Postives = 54/99 (54.55%), Query Frame = 3
Query:  171 MCHNVGYNKMVLPNFIQHEYMEEAIAHSRVWLSLVKSQCHLDVRKFLCSLYAPVCITNKRIQKVPPCRELCIIVKEACLPSMKMYGFNWPEIMKCSKFP 467
MC +GYN PN + HE +EA + LV+ +C D++ FLCS+Y P+C+ + + +P CR +C + C P M+ Y F WPE M C P
Sbjct: 71 MCRGIGYNMTSFPNEMNHETQDEAGLEVHQFWPLVEIKCSPDLKFFLCSMYTPICLEDYH-KPLPVCRSVCERARSGCAPIMQQYSFEWPERMACEHLP 168
BLAST of sfrp-1 vs. RefSeq Drosophila melanogaster
Match: gi|24666637|ref|NP_730389.1| (frizzled 2, isoform B [Drosophila melanogaster])

HSP 1 Score: 83.9593 bits (206), Expect = 3.63181e-17
Identity = 37/99 (37.37%), Postives = 54/99 (54.55%), Query Frame = 3
Query:  171 MCHNVGYNKMVLPNFIQHEYMEEAIAHSRVWLSLVKSQCHLDVRKFLCSLYAPVCITNKRIQKVPPCRELCIIVKEACLPSMKMYGFNWPEIMKCSKFP 467
MC +GYN PN + HE +EA + LV+ +C D++ FLCS+Y P+C+ + + +P CR +C + C P M+ Y F WPE M C P
Sbjct: 71 MCRGIGYNMTSFPNEMNHETQDEAGLEVHQFWPLVEIKCSPDLKFFLCSMYTPICLEDYH-KPLPVCRSVCERARSGCAPIMQQYSFEWPERMACEHLP 168
The following BLAST results are available for this feature:
BLAST of sfrp-1 vs. uniprot
Analysis Date: 2016-03-07 (Dugesia dorotocephala BLASTX Swissprot Uniprot)
Total hits: 5
Match NameE-valueIdentityDescription
gi|61216765|sp|P97299|SFRP2_MOUSE9.361320e-3737.00RecName: Full=Secreted frizzled-related protein 2;... [more]
gi|61216791|sp|Q863H1|SFRP2_CANFA1.898030e-3637.00RecName: Full=Secreted frizzled-related protein 2;... [more]
gi|61216828|sp|Q96HF1|SFRP2_HUMAN1.918700e-3637.00RecName: Full=Secreted frizzled-related protein 2;... [more]
gi|341942099|sp|Q8C4U3|SFRP1_MOUSE5.873870e-3639.78RecName: Full=Secreted frizzled-related protein 1;... [more]
gi|61216839|sp|Q9DEQ4|SFRP1_CHICK9.320620e-3636.00RecName: Full=Secreted frizzled-related protein 1;... [more]
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BLAST of sfrp-1 vs. Smed Unigenes AA
Analysis Date: 2016-03-08 (Dugesia dorotocephala BLASTX Schmidtea mediterranea)
Total hits: 5
Match NameE-valueIdentityDescription
SMU150012743.327530e-13569.90Asxlregen_comp63361_c0_seq1|m.13574|m.6037[more]
SMU150405241.035580e-5537.75dd_smedV4_8832_0_1|m.39951|m.18186[more]
SMU150308838.798700e-3732.22SmedSxlregen_c55322_g1_i1|m.6956|m.30359[more]
SMU150010549.958340e-2436.60Asxlregen_comp62015_c0_seq1|m.11130|m.22104[more]
SMU150361997.941900e-2140.29SmedSxlregen_c90692_g1_i1|m.42870|m.18187[more]
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BLAST of sfrp-1 vs. RefSeq Human
Analysis Date: 2016-03-08 (Dugesia dorotocephala BLASTX Human)
Total hits: 5
Match NameE-valueIdentityDescription
gi|48475052|ref|NP_003004.1|7.241330e-3737.00secreted frizzled-related protein 2 precursor [Hom... [more]
gi|56117838|ref|NP_003003.3|2.820710e-3539.25secreted frizzled-related protein 1 precursor [Hom... [more]
gi|188528609|ref|NP_003006.2|5.261820e-3332.22secreted frizzled-related protein 5 precursor [Hom... [more]
gi|4503825|ref|NP_003496.1|2.633710e-2237.98frizzled-1 [Homo sapiens][more]
gi|4503833|ref|NP_003498.1|2.136670e-2037.90frizzled-7 precursor [Homo sapiens][more]
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BLAST of sfrp-1 vs. RefSeq Drosophila melanogaster
Analysis Date: 2016-03-08 (Dugesia dorotocephala BLASTX Drosophila melanogaster)
Total hits: 5
Match NameE-valueIdentityDescription
gi|442632294|ref|NP_001261836.1|3.933560e-2046.15frizzled, isoform C [Drosophila melanogaster][more]
gi|17864440|ref|NP_524812.1|4.178340e-2046.15frizzled, isoform A [Drosophila melanogaster][more]
gi|442633302|ref|NP_001262037.1|3.551250e-1737.37frizzled 2, isoform F [Drosophila melanogaster][more]
gi|17737633|ref|NP_524155.1|3.631810e-1737.37frizzled 2, isoform A [Drosophila melanogaster][more]
gi|24666637|ref|NP_730389.1|3.631810e-1737.37frizzled 2, isoform B [Drosophila melanogaster][more]
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Sequences
The following sequences are available for this feature:

mRNA sequence

>Ddo_009225 ID=Ddo_009225|Name=sfrp-1|organism=Dugesia dorotocephala|type=mRNA|length=1153bp
ATTTAATCGCATTTTCAAATGATATTGGTATTCGGGGAATGATCACAATT
CTACCTCTAGGTTTATTGTTGTCGTTGTTTTCCAATGGGAATTGCTTTAT
TGGCGATTGGGAATCGTTTCGAAGCGGTTATACGACGGATCAATGTTACA
AAGTTCCCGAAAACTTTTCAATGTGTCATAATGTTGGTTATAACAAAATG
GTTCTACCTAATTTTATACAACACGAGTATATGGAAGAAGCGATAGCTCA
TTCTCGAGTATGGTTAAGTCTAGTTAAGTCTCAATGTCATCTTGATGTGA
GAAAGTTTTTGTGTTCTTTATATGCTCCTGTATGTATTACAAATAAAAGA
ATACAAAAAGTTCCCCCATGTCGAGAACTATGCATAATTGTCAAGGAAGC
TTGTTTACCAAGTATGAAGATGTACGGCTTTAACTGGCCGGAGATTATGA
AATGTTCCAAATTTCCACCAGTACAAAATGCATTATGTATACCGAAAACA
ACAGTGAAAAAAAAAAATTGTGAATTATGTGTTAAAAATGCGCCTTACGA
AGTGATAGCAAATAGATTTTGTTTATCTCCCATAGTAATAAGGGCTAAAA
TCAAACGAATTATTCCCAAAGAATCGGGGTTTCAAATAGTTTTGCATCAA
AAATCCAAATTTTTAAAATTTCAATCAAATTCTAGTCGGGATTCCGTCAA
TTTATGGCTGAAATGTAATTGTTTGAATCTGAAATTTCAGCAAAGAGCCC
TTCGAGGAAGGTGGATCATCATGGCTCGAATCGTCGAAGATAGATTTGTT
GTGAATTTCATTTCCAAATGGAAAAAAAAGAAAGAGGAATTTAAAAATTC
TATTAGAATTATTCAGAAATTCGGAAATGTTGTTTGTAAATCGAAGCTTA
AGGATGGCATAAGTCTCCAGGAACGATATGTGGCCTATATGAAGATGAAT
AATAAAACCAATTATCAAAATCAGTTGAAACAACAAACGAGAAAGTTTAA
GAAAAGAAAACAAAATCAACAACGAAGAATTCCTTAAAATTTTTCCTTCT
TGGTTTTTTTTAAATATAAAATATTAATTGCTTTATTAATTATGAAACAT
TGCATCGATTAAAGACTTAACATTATTTTTATTATGTAAACTTTATATGT
TCA

Design Primers for sfrp-1

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protein sequence

>Ddo_009225-protein ID=Ddo_009225-protein|Name=sfrp-1|organism=Dugesia dorotocephala|type=polypeptide|length=345bp
LIAFSNDIGIRGMITILPLGLLLSLFSNGNCFIGDWESFRSGYTTDQCYK
VPENFSMCHNVGYNKMVLPNFIQHEYMEEAIAHSRVWLSLVKSQCHLDVR
KFLCSLYAPVCITNKRIQKVPPCRELCIIVKEACLPSMKMYGFNWPEIMK
CSKFPPVQNALCIPKTTVKKKNCELCVKNAPYEVIANRFCLSPIVIRAKI
KRIIPKESGFQIVLHQKSKFLKFQSNSSRDSVNLWLKCNCLNLKFQQRAL
RGRWIIMARIVEDRFVVNFISKWKKKKEEFKNSIRIIQKFGNVVCKSKLK
DGISLQERYVAYMKMNNKTNYQNQLKQQTRKFKKRKQNQQRRIP*
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coding sequence

>Ddo_009225.3.1037 ID=Ddo_009225.3.1037|Name=Ddo_009225.3.1037|organism=Dugesia dorotocephala|type=CDS|length=1035bp
TTAATCGCATTTTCAAATGATATTGGTATTCGGGGAATGATCACAATTCT
ACCTCTAGGTTTATTGTTGTCGTTGTTTTCCAATGGGAATTGCTTTATTG
GCGATTGGGAATCGTTTCGAAGCGGTTATACGACGGATCAATGTTACAAA
GTTCCCGAAAACTTTTCAATGTGTCATAATGTTGGTTATAACAAAATGGT
TCTACCTAATTTTATACAACACGAGTATATGGAAGAAGCGATAGCTCATT
CTCGAGTATGGTTAAGTCTAGTTAAGTCTCAATGTCATCTTGATGTGAGA
AAGTTTTTGTGTTCTTTATATGCTCCTGTATGTATTACAAATAAAAGAAT
ACAAAAAGTTCCCCCATGTCGAGAACTATGCATAATTGTCAAGGAAGCTT
GTTTACCAAGTATGAAGATGTACGGCTTTAACTGGCCGGAGATTATGAAA
TGTTCCAAATTTCCACCAGTACAAAATGCATTATGTATACCGAAAACAAC
AGTGAAAAAAAAAAATTGTGAATTATGTGTTAAAAATGCGCCTTACGAAG
TGATAGCAAATAGATTTTGTTTATCTCCCATAGTAATAAGGGCTAAAATC
AAACGAATTATTCCCAAAGAATCGGGGTTTCAAATAGTTTTGCATCAAAA
ATCCAAATTTTTAAAATTTCAATCAAATTCTAGTCGGGATTCCGTCAATT
TATGGCTGAAATGTAATTGTTTGAATCTGAAATTTCAGCAAAGAGCCCTT
CGAGGAAGGTGGATCATCATGGCTCGAATCGTCGAAGATAGATTTGTTGT
GAATTTCATTTCCAAATGGAAAAAAAAGAAAGAGGAATTTAAAAATTCTA
TTAGAATTATTCAGAAATTCGGAAATGTTGTTTGTAAATCGAAGCTTAAG
GATGGCATAAGTCTCCAGGAACGATATGTGGCCTATATGAAGATGAATAA
TAAAACCAATTATCAAAATCAGTTGAAACAACAAACGAGAAAGTTTAAGA
AAAGAAAACAAAATCAACAACGAAGAATTCCTTAA
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Gene Groups
sfrp-1 is similar in sequence to the genes of this group: GG7656
Gene NameGene ID
SMU15001274SMU15001274
sfrp-1Ddo_009225
sfrp-1Gsp_013592
sfrp-1Pgr_015361
sfrp-1Pmo_009874

Gene Group Protein Sequences

>SMU15001274

MEMTKIFPLSLLLFISNVNSFIGDWQAFQSGYTIDQCYQIPDNFTLCSNV
GYRLMVLPNYIQHESIEEAAQHSKVWMGLVNTQCHVDIKKFICSLYAPVC
ISNQRNQKVPPCRELCVTVKESCLPSMKMYGFDWPTIMKCSKFPQFKNSL
CIPKTVVPGKKCDLCMKIASYEVIANRFCLSPIVIRAKIKRIIPTSGNAI
QIILQKKSKFLKFQANFSQNALELNLKCNCTNLKFKQRALKGRWIIMAQI
DSDNKAVVNFISKWKRKKAEFKHSMKIIQNFGHIVCKSKLPDGISLRERY
AAYLKMNNQLKYSNERKLQTRKFRKQKSRKSVKPNNRSAGIS*
>Ddo_009225 sfrp-1
LIAFSNDIGIRGMITILPLGLLLSLFSNGNCFIGDWESFRSGYTTDQCYK
VPENFSMCHNVGYNKMVLPNFIQHEYMEEAIAHSRVWLSLVKSQCHLDVR
KFLCSLYAPVCITNKRIQKVPPCRELCIIVKEACLPSMKMYGFNWPEIMK
CSKFPPVQNALCIPKTTVKKKNCELCVKNAPYEVIANRFCLSPIVIRAKI
KRIIPKESGFQIVLHQKSKFLKFQSNSSRDSVNLWLKCNCLNLKFQQRAL
RGRWIIMARIVEDRFVVNFISKWKKKKEEFKNSIRIIQKFGNVVCKSKLK
DGISLQERYVAYMKMNNKTNYQNQLKQQTRKFKKRKQNQQRRIP*
>Gsp_013592 sfrp-1
MVIIFRFTFILFVFNVNCFIGDWQSFQSGYTIDQCYHIPDNFSLCRNVGY
NRMVLPNYIQHESIEEAVQHSRVWMGLVNTQCHIDIRKFICSLYAPVCIS
SQRVQKVPPCRELCVTVKESCLPSMKMYGFDWPTIMKCSKFPQFQNSLCI
PRTLVPEKNCDLCIKNPSYEVIANRFCLSPIVIRAKIKRIIPIGSKTMQI
VLQKKSKFLKFFANFSQTDLNLRLKCNCTNLKFKQRALKGRWIIMAKVNQ
NEAVVNFITKWKRKKAEFKHSMKIIQNFGHIVCKSKLPDGISLRERYAAY
LKMNNKIKYSNNNNKSKQQTRRSKKPINTRSSSIS*
>Pgr_015361 sfrp-1
LFLFFIFYLHISCFLGDWQQFQNGYSTEQCFKIPDNLTLCLNVGYKRMIL
PNYIQHEYLDEAVQHSKVWIGLVNSHCHEDIRKFLCSLYAPVCINNMRIQ
KVPPCKELCVSVKEACLPSMKLFGFEWPNIMKCSLFPSVRNSLCIPSTVS
KGKKCRPCVKSSSYEVMANKFCLSNIVIRAKIKRIVKEGNNGFKIELGQK
TGFLKFQSDFTRNSLKILLQCNCTRLKFEKRALKGKWLIMVNIVDNQPVV
NFITKWKRKNTNFRYSINVLRKFGNELCRLNLPNNSDGRTSMLKRYLAYA
KMNNITQFKNRKNRNNNSKENKKPKKSWTTQKKNAYKN*
>Pmo_009874 sfrp-1
MCILSLFFFNIFYLQIACFLGDWQQFQNGYSAEQCYKIPDNLTLCLNVGY
KRMILPNYIQHEYLEETVQHSKVWIGLVNSNCHEDIKKFLCSLYAPVCIY
NMKIQKVPPCKELCLSVKESCLPSMKLFGFEWPNIMECSLFPSGRNSLCI
PSTIHKDKKCRSCVKSASYEVMANKFCLSNIVIRGKIRRITAKKDNGYII
DLSQKSRFLKFQSNQSQSSLQIWLQCNCTKLKFENKALKGKWLIMVNIVK
GQPIVNFITKWKRRNIDFRNSINVLRKFGNELCRLNLPNNSDGRTSMLKR
YLAYAKMKNRNKASNKTK*

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